{"id":927,"date":"2026-10-20T16:34:38","date_gmt":"2026-10-20T19:34:38","guid":{"rendered":"https:\/\/order-science.com\/?page_id=927"},"modified":"2026-10-20T16:56:10","modified_gmt":"2026-10-20T19:56:10","slug":"doltendix-en","status":"publish","type":"page","link":"https:\/\/order-science.com\/en\/doltendix-en\/","title":{"rendered":"Doltendix"},"content":{"rendered":"\n<meta charset=\"UTF-8\">\n<meta name=\"viewport\" content=\"width=device-width, initial-scale=1.0\">\n<title>Doltendix\u00ae | Dietary supplement for tendons and ligaments \u2014 Kolinpharma<\/title>\n<meta name=\"description\" content=\"Doltendix\u00ae: tendon-specific collagen, astaxanthin, trans-resveratrol and vitamin C. The highest dose of bioactive collagen peptides available on the market. Patented in Italy and China.\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.googleapis.com\">\n<link rel=\"preconnect\" href=\"https:\/\/fonts.gstatic.com\" crossorigin=\"\">\n<link href=\"https:\/\/fonts.googleapis.com\/css2?family=Fraunces:ital,opsz,wght@0,9..144,400;0,9..144,500;0,9..144,600;0,9..144,700;1,9..144,500;1,9..144,600&amp;family=Inter:wght@400;500;600;700;800&amp;display=swap\" rel=\"stylesheet\">\n<style>\n\/* ============ TOKENS ============ *\/\n:root{\n  --blue-900:#052A3D;\n  --blue-700:#075D86;\n  --blue-600:#0089CC;\n  --blue-550:#1596D6;\n  --blue-500:#29ABE8;\n  --blue-200:#BFE4F6;\n  --blue-100:#E8F5FC;\n  --blue-50:#F5FBFE;\n  --ink:#122130;\n  --slate:#54697A;\n  --slate-light:#7C8D9B;\n  --coral:#B9504A;\n  --coral-100:#F8E9E7;\n  --green:#1F8F53;\n  --green-100:#E7F6EC;\n  --paper:#F6FAFC;\n  --line:#E2ECF2;\n  --white:#FFFFFF;\n  --radius-lg:28px;\n  --radius-md:18px;\n  --radius-sm:12px;\n  --shadow-soft:0 20px 60px -25px rgba(5,42,61,0.35);\n  --shadow-card:0 12px 32px -18px rgba(5,42,61,0.25);\n  --maxw:1200px;\n}\n*,*::before,*::after{box-sizing:border-box;}\n\/* prevent grid\/flex children (esp. images) from forcing horizontal overflow on mobile *\/\n.hero-grid,.mech-grid,.why-grid,.comp-grid,.gallery-grid,.problem-grid,.indications-grid,\n.cert-grid,.flow-row,.grid-2,.stat-row,.badge-row,.hero-ctas,.dose-phase{min-width:0;}\n.hero-grid > *,.mech-grid > *,.why-grid > *,.comp-grid > *,.gallery-grid > *,.problem-grid > *,\n.indications-grid > *,.cert-grid > *,.flow-row > *,.grid-2 > *,.stat-row > *,.dose-phase > *{min-width:0;}\nhtml{scroll-behavior:smooth;overflow-x:hidden;max-width:100%;}\nbody{\n  margin:0;\n  font-family:'Inter',-apple-system,BlinkMacSystemFont,sans-serif;\n  color:var(--ink);\n  background:var(--white);\n  -webkit-font-smoothing:antialiased;\n  line-height:1.6;\n  overflow-x:hidden;\n  max-width:100%;\n}\nimg{max-width:100%;display:block;}\na{color:inherit;}\n.container{max-width:var(--maxw);margin:0 auto;padding:0 28px;}\nh1,h2,h3,h4{\n  font-family:'Fraunces',serif;\n  font-weight:600;\n  line-height:1.15;\n  margin:0 0 .5em;\n  color:var(--blue-900);\n  letter-spacing:-0.01em;\n}\nh1{font-size:clamp(30px,4.6vw,58px);}\nh2{font-size:clamp(24px,3.4vw,38px);}\nh3{font-size:clamp(19px,2.4vw,24px);}\nh4{font-size:clamp(16px,1.8vw,18px);}\nh1 em, h2 em, h3 em{font-style:italic;font-weight:500;color:var(--blue-600);}\np{margin:0 0 1em;color:var(--slate);}\n.eyebrow{\n  display:flex;align-items:center;gap:8px;flex-wrap:wrap;\n  font-size:12.5px;font-weight:700;letter-spacing:.14em;text-transform:uppercase;\n  color:var(--blue-600);margin-bottom:14px;max-width:100%;\n}\n.eyebrow::before{content:\"\";width:22px;height:2px;flex:none;background:var(--blue-500);border-radius:2px;}\nsection{position:relative;}\n.section-pad{padding:100px 0;}\n@media(max-width:900px){.section-pad{padding:68px 0;}}\n.section-head{max-width:680px;margin:0 0 48px;}\n.section-head.center{margin-left:auto;margin-right:auto;text-align:center;}\n.section-head p{font-size:17px;}\n\n\/* \u2500\u2500 Language switch (ES \/ EN) \u2500\u2500 *\/\n.lang-switch{\n  max-width:var(--maxw);margin:-40px auto 22px;padding:0 28px;\n  display:flex;justify-content:flex-end;gap:6px;position:relative;z-index:3;\n}\n.lang-switch a,.lang-switch span{\n  display:inline-flex;align-items:center;justify-content:center;min-width:42px;\n  padding:6px 12px;border-radius:999px;border:1px solid var(--line);background:#fff;\n  font-family:'Inter',sans-serif;font-size:12.5px;font-weight:700;letter-spacing:.06em;\n  color:var(--blue-900);text-decoration:none !important;transition:border-color .2s,color .2s;\n}\n.lang-switch a:hover{border-color:var(--blue-500);color:var(--blue-600);}\n.lang-switch .active{background:var(--blue-600);border-color:var(--blue-600);color:#fff;}\n@media(max-width:960px){.lang-switch{justify-content:center;margin-top:-36px;}}\n\n\/* Buttons *\/\n.btn{\n  display:inline-flex;align-items:center;justify-content:center;gap:8px;\n  padding:15px 28px;border-radius:999px;font-weight:600;font-size:15px;\n  text-decoration:none !important;cursor:pointer;border:1.5px solid transparent;\n  transition:transform .18s ease, box-shadow .18s ease, background .18s ease, color .18s ease;\n  font-family:'Inter',sans-serif;position:relative;overflow:hidden;\n}\n.btn::after{\n  content:\"\";position:absolute;top:0;left:-60%;width:40%;height:100%;\n  background:linear-gradient(120deg,transparent,rgba(255,255,255,.5),transparent);\n  transform:skewX(-20deg);transition:left .6s ease;\n}\n.btn:hover::after{left:130%;}\n.btn-primary{background:var(--blue-600);color:#fff;box-shadow:0 10px 26px -10px rgba(0,137,204,.55);}\n.btn-primary:hover{background:var(--blue-700);transform:translateY(-2px);box-shadow:0 16px 30px -12px rgba(0,137,204,.6);}\n.btn-ghost{background:transparent;color:var(--blue-900);border-color:var(--line);}\n.btn-ghost:hover{border-color:var(--blue-500);color:var(--blue-600);transform:translateY(-2px);}\n.btn-white{background:#fff;color:var(--blue-700);}\n.btn-white:hover{transform:translateY(-2px);box-shadow:0 14px 30px -14px rgba(0,0,0,.35);}\n\n\/* \u2500\u2500 Buy button (label + price stacked) \u2500\u2500 *\/\n.btn-buy{flex-direction:column;gap:2px;padding-top:13px;padding-bottom:13px;line-height:1.15;}\n.btn-buy .cta-label,.btn-buy .cta-price{text-decoration:none !important;}\n.btn-buy .cta-label{font-weight:700;}\n.btn-buy .cta-price{font-family:'Inter',sans-serif;font-size:12px;font-weight:700;letter-spacing:.2px;}\n.btn-primary.btn-buy .cta-price{color:rgba(255,255,255,.85);}\n.btn-white.btn-buy .cta-price{color:var(--blue-600);}\n\n\/* \u2500\u2500 Quantity selector \u2500\u2500 *\/\n.buy-row{display:flex;align-items:stretch;gap:14px;flex-wrap:wrap;}\n.buy-row.center{justify-content:center;}\n.qty-selector{\n  display:inline-flex;align-items:stretch;\n  background:#fff;border:1.5px solid var(--line);border-radius:999px;\n  overflow:hidden;flex-shrink:0;\n}\n.qty-btn{\n  width:42px;height:100% !important;align-self:stretch !important;\n  padding:0 !important;margin:0 !important;line-height:1 !important;\n  border:none;background:transparent;color:var(--blue-900);\n  font-family:'Inter',sans-serif;font-size:18px;font-weight:700;cursor:pointer;\n  transition:background .2s;\n  display:flex !important;align-items:center !important;justify-content:center !important;\n  box-sizing:border-box !important;\n}\n.qty-btn:hover{background:var(--blue-100);}\n.qty-input{\n  width:44px;height:100% !important;align-self:stretch !important;\n  padding:0 !important;margin:0 !important;line-height:normal !important;\n  border:none;border-top:none !important;border-bottom:none !important;\n  border-left:1px solid var(--line);border-right:1px solid var(--line);\n  text-align:center;font-family:'Inter',sans-serif;font-weight:700;font-size:15px;\n  color:var(--blue-900);background:transparent !important;box-sizing:border-box !important;\n  vertical-align:middle;-moz-appearance:textfield;-webkit-appearance:none;appearance:none;\n}\n.qty-input::-webkit-outer-spin-button,.qty-input::-webkit-inner-spin-button{-webkit-appearance:none;margin:0;}\n.qty-selector-cta{background:rgba(255,255,255,.08);border-color:rgba(255,255,255,.3);}\n.qty-selector-cta .qty-btn{color:#fff;}\n.qty-selector-cta .qty-btn:hover{background:rgba(255,255,255,.14);}\n.qty-selector-cta .qty-input{color:#fff;border-left-color:rgba(255,255,255,.25);border-right-color:rgba(255,255,255,.25);}\n.doltendix-buy-link.is-loading{opacity:.72;pointer-events:none;}\n@media(max-width:480px){\n  .buy-row{flex-direction:column;align-items:stretch;}\n  .buy-row .qty-selector{align-self:center;}\n}\n\n\/* ============ HERO ============ *\/\n.hero{\n  background:linear-gradient(180deg,#F5FBFE 0%, #EAF6FC 55%, #ffffff 100%);\n  padding:64px 0 0;\n  overflow:hidden;\n}\n.hero-grid{\n  display:grid;grid-template-columns:1.05fr .95fr;gap:40px;align-items:start;\n  max-width:var(--maxw);margin:0 auto;padding:0 28px;\n}\n@media(max-width:960px){.hero-grid{grid-template-columns:1fr;text-align:center;}}\n.hero h1{font-size:clamp(30px,4.6vw,58px);margin-bottom:22px;}\n.hero-sub{font-size:18px;max-width:520px;}\n@media(max-width:960px){.hero-sub{margin-left:auto;margin-right:auto;}}\n.hero-ctas{display:flex;gap:14px;margin:30px 0 34px;flex-wrap:wrap;}\n@media(max-width:960px){.hero-ctas{justify-content:center;}}\n.badge-row{display:flex;flex-wrap:wrap;gap:10px;}\n@media(max-width:960px){.badge-row{justify-content:center;}}\n.badge{\n  display:flex;align-items:center;gap:7px;\n  background:#fff;border:1px solid var(--line);padding:9px 14px;border-radius:999px;\n  font-size:12.5px;font-weight:700;color:var(--blue-900);box-shadow:0 6px 16px -12px rgba(5,42,61,.3);\n}\n.badge svg{width:14px;height:14px;flex:none;color:var(--blue-600);}\n.hero-visual{position:relative;display:flex;justify-content:center;align-items:center;min-height:420px;}\n.hero-visual::before{\n  content:\"\";position:absolute;width:120%;height:120%;\n  background:radial-gradient(circle,var(--blue-200) 0%, transparent 65%);\n  opacity:.6;z-index:0;\n}\n.hero-photo{\n  position:relative;z-index:1;width:100%;max-width:420px;aspect-ratio:4\/5;\n  border-radius:var(--radius-lg);object-fit:cover;object-position:center 20%;\n  box-shadow:var(--shadow-soft);\n}\n.hero-product-img{\n  position:absolute;z-index:2;right:2%;bottom:-6%;\n  max-width:min(260px,46%);width:100%;\n  filter:drop-shadow(0 30px 40px rgba(5,42,61,.3));animation:float 5s ease-in-out infinite;\n}\n@media(max-width:960px){\n  .hero-visual{min-height:0;margin-top:8px;}\n  .hero-photo{max-width:340px;margin:0 auto;display:block;}\n  .hero-product-img{right:-4%;bottom:-8%;}\n}\n@media(max-width:480px){\n  .hero-photo{aspect-ratio:3\/4;}\n  .hero-product-img{max-width:min(180px,44%);}\n}\n@keyframes float{0%,100%{transform:translateY(0px) rotate(0deg);}50%{transform:translateY(-14px) rotate(-1deg);}}\n.hero-strip{\n  margin-top:56px;border-top:1px solid var(--line);background:#fff;\n}\n.stat-row{\n  display:grid;grid-template-columns:repeat(5,1fr);\n  max-width:var(--maxw);margin:0 auto;padding:0 28px;\n}\n.stat-cell{text-align:center;padding:26px 10px;border-right:1px solid var(--line);}\n.stat-cell:last-child{border-right:none;}\n.stat-num{font-family:'Fraunces',serif;font-weight:600;font-size:clamp(20px,2.6vw,30px);color:var(--blue-600);}\n.stat-label{font-size:12px;color:var(--slate);font-weight:600;margin-top:4px;letter-spacing:.02em;}\n@media(max-width:900px){\n  .stat-row{grid-template-columns:repeat(2,1fr);}\n  .stat-cell{border-right:none;border-bottom:1px solid var(--line);}\n}\n\n\/* ============ CLOSE-UP GALLERY ============ *\/\n.gallery-grid{display:grid;grid-template-columns:repeat(3,1fr);gap:22px;}\n@media(max-width:800px){.gallery-grid{grid-template-columns:1fr;}}\n.gallery-card{\n  background:var(--paper);border-radius:var(--radius-md);overflow:hidden;border:1px solid var(--line);\n  display:flex;flex-direction:column;transition:transform .35s cubic-bezier(.2,.8,.2,1), box-shadow .35s ease;\n}\n.gallery-card:hover{transform:translateY(-6px);box-shadow:var(--shadow-card);}\n.gallery-card .imgwrap{aspect-ratio:4\/3.6;display:flex;align-items:center;justify-content:center;padding:26px;background:#fff;overflow:hidden;}\n.gallery-card .imgwrap img{max-height:100%;object-fit:contain;transition:transform .5s ease;}\n.gallery-card:hover .imgwrap img{transform:scale(1.06);}\n.gallery-card .cap{padding:16px 20px 20px;font-weight:600;font-size:14.5px;color:var(--blue-900);}\n\n\/* ============ PROBLEM \/ SYMPTOMS ============ *\/\n.problem-sec{background:var(--blue-900);color:#fff;}\n.problem-sec h2{color:#fff;}\n.problem-sec .section-head p{color:#B9D6E4;}\n.problem-grid{display:grid;grid-template-columns:1fr 1fr;gap:0;align-items:stretch;}\n@media(max-width:900px){.problem-grid{grid-template-columns:1fr;}}\n.problem-photos{display:grid;grid-template-columns:1fr 1fr;gap:16px;}\n.problem-photos figure{margin:0;border-radius:var(--radius-md);overflow:hidden;background:linear-gradient(160deg,#0B3A52,#0C4863);position:relative;aspect-ratio:3\/4;}\n.problem-photos img{width:100%;height:100%;object-fit:cover;object-position:center;transition:transform .6s cubic-bezier(.2,.8,.2,1);}\n.problem-photos figure:hover img{transform:scale(1.06);}\n.symptom-list{display:flex;flex-direction:column;gap:0;margin-top:8px;}\n.symptom-item{\n  display:flex;align-items:center;gap:16px;padding:20px 0;border-bottom:1px solid rgba(255,255,255,.12);\n  font-family:'Fraunces',serif;font-size:clamp(20px,2.4vw,28px);font-weight:500;color:#fff;\n}\n.symptom-item:first-child{padding-top:0;}\n.symptom-item .dot{width:9px;height:9px;border-radius:50%;background:var(--coral);flex:none;}\n\n\/* ============ MECHANISM (llega \/ actua) ============ *\/\n.mech-grid{display:grid;grid-template-columns:1fr 1fr;gap:56px;align-items:center;}\n@media(max-width:900px){.mech-grid{grid-template-columns:1fr;gap:40px;}}\n.cycle-wrap{position:relative;width:100%;max-width:420px;aspect-ratio:1;margin:0 auto;padding:44px 54px;}\n.cycle-ring{\n  position:absolute;inset:44px 54px;border-radius:50%;border:2px dashed var(--blue-200);\n}\n.cycle-center{\n  position:absolute;top:50%;left:50%;transform:translate(-50%,-50%);\n  text-align:center;background:#fff;border-radius:50%;width:42%;height:42%;\n  display:flex;flex-direction:column;align-items:center;justify-content:center;\n  box-shadow:var(--shadow-card);border:1px solid var(--line);z-index:2;\n}\n.cycle-center img{height:20px;margin-bottom:6px;}\n.cycle-center b{font-family:'Fraunces',serif;font-size:clamp(16px,4vw,22px);color:var(--blue-600);font-weight:600;}\n.cycle-center span{font-size:11.5px;color:var(--slate);}\n.cycle-node{\n  position:absolute;font-weight:700;font-size:12.5px;color:var(--green);\n  background:var(--green-100);padding:7px 12px;border-radius:14px;\n  box-shadow:0 6px 16px -10px rgba(31,143,83,.4);\n  width:112px;text-align:center;line-height:1.25;\n}\n.cycle-node.n1{top:0;left:50%;transform:translate(-50%,0);}\n.cycle-node.n2{top:44%;right:0;transform:translateY(-50%);}\n.cycle-node.n3{bottom:0;left:0;}\n@media(max-width:480px){\n  .cycle-wrap{padding:34px 40px;max-width:320px;}\n  .cycle-ring{inset:34px 40px;}\n  .cycle-node{font-size:10.5px;padding:6px 9px;width:92px;border-radius:12px;}\n  .cycle-center b{font-size:16px;}\n  .cycle-center span{font-size:10.5px;}\n}\n\n.action-card{\n  background:var(--blue-50);border:1px solid var(--line);border-radius:var(--radius-md);\n  padding:32px;\n}\n.action-card .kpi-row{display:flex;gap:28px;margin-top:22px;flex-wrap:wrap;}\n.kpi{flex:1;min-width:130px;}\n.kpi b{display:block;font-family:'Fraunces',serif;font-size:26px;color:var(--coral);font-weight:600;}\n.kpi span{font-size:13px;color:var(--slate);}\n.stop-diagram{display:flex;align-items:center;justify-content:center;gap:18px;margin:26px 0;flex-wrap:wrap;}\n.stop-pill{\n  display:flex;flex-direction:column;align-items:center;gap:6px;text-align:center;font-size:13px;font-weight:700;\n}\n.stop-pill .circle{\n  width:64px;height:64px;border-radius:50%;display:flex;align-items:center;justify-content:center;\n  background:var(--coral-100);color:var(--coral);font-family:'Fraunces',serif;font-size:13px;font-weight:700;\n  border:2px solid var(--coral);\n}\n.stop-arrow{color:var(--slate-light);font-size:20px;}\n.stop-center{\n  width:78px;height:78px;border-radius:50%;background:var(--blue-900);color:#fff;\n  display:flex;align-items:center;justify-content:center;font-weight:800;font-size:13px;letter-spacing:.04em;\n}\n\n\/* ============ WHY CHOOSE (dose + collagen shift) ============ *\/\n.why-grid{display:grid;grid-template-columns:1fr 1fr;gap:32px;}\n@media(max-width:900px){.why-grid{grid-template-columns:1fr;}}\n.why-card{\n  background:#fff;border:1px solid var(--line);border-radius:var(--radius-lg);padding:36px;\n  box-shadow:var(--shadow-card);transition:transform .35s cubic-bezier(.2,.8,.2,1);\n}\n.why-card:hover{transform:translateY(-6px);}\n.why-card h3{font-size:22px;}\n.tag{\n  display:inline-block;font-size:11.5px;font-weight:800;letter-spacing:.08em;text-transform:uppercase;\n  color:var(--blue-600);background:var(--blue-100);padding:5px 12px;border-radius:999px;margin-bottom:14px;\n}\n.why-card img{border-radius:var(--radius-sm);margin-top:18px;width:100%;}\n.before-after{display:flex;gap:18px;margin-top:22px;}\n.ba-col{flex:1;text-align:center;padding:18px 10px;border-radius:var(--radius-sm);}\n.ba-col.before{background:var(--coral-100);}\n.ba-col.after{background:var(--green-100);}\n.ba-col b{display:block;font-family:'Fraunces',serif;font-size:17px;margin-bottom:4px;}\n.ba-col.before b{color:var(--coral);}\n.ba-col.after b{color:var(--green);}\n.ba-col span{font-size:12.5px;color:var(--slate);}\n\n\/* ============ COMPOSITION CARDS ============ *\/\n.comp-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:20px;}\n@media(max-width:960px){.comp-grid{grid-template-columns:repeat(2,1fr);}}\n@media(max-width:560px){.comp-grid{grid-template-columns:1fr;}}\n.comp-card{\n  border:1px solid var(--line);border-radius:var(--radius-md);padding:28px 24px;background:#fff;\n  transition:box-shadow .2s, transform .2s;\n}\n.comp-card:hover{box-shadow:var(--shadow-card);transform:translateY(-3px);}\n.comp-icon{\n  width:46px;height:46px;border-radius:12px;background:var(--blue-100);color:var(--blue-600);\n  display:flex;align-items:center;justify-content:center;margin-bottom:16px;font-size:20px;\n}\n.comp-card .dose{font-family:'Fraunces',serif;font-weight:600;font-size:26px;color:var(--blue-600);margin:6px 0 12px;}\n.comp-card h4{font-size:17px;margin-bottom:2px;}\n.comp-card .sub{font-size:12.5px;color:var(--slate-light);font-weight:600;margin-bottom:10px;}\n.comp-card ul{margin:0;padding-left:18px;font-size:13.5px;color:var(--slate);}\n.comp-card li{margin-bottom:5px;}\n\n\/* ============ EVIDENCE \/ ACCORDION ============ *\/\n.evidence-list{display:flex;flex-direction:column;gap:14px;}\ndetails.ev-item{\n  border:1px solid var(--line);border-radius:var(--radius-md);overflow:hidden;background:#fff;\n}\ndetails.ev-item[open]{box-shadow:var(--shadow-card);}\ndetails.ev-item summary{\n  list-style:none;cursor:pointer;padding:22px 26px;display:flex;align-items:center;justify-content:space-between;\n  gap:20px;font-family:'Fraunces',serif;font-weight:600;font-size:18px;color:var(--blue-900);\n}\ndetails.ev-item summary::-webkit-details-marker{display:none;}\n.ev-plus{\n  width:30px;height:30px;border-radius:50%;border:1.5px solid var(--blue-300,var(--blue-500));flex:none;\n  display:flex;align-items:center;justify-content:center;color:var(--blue-600);font-size:18px;font-weight:400;\n  transition:transform .2s;\n}\ndetails.ev-item[open] .ev-plus{transform:rotate(45deg);}\n.ev-body{padding:0 26px 30px;}\n.ev-meta{font-size:12.5px;color:var(--slate-light);font-weight:600;margin-bottom:14px;text-transform:uppercase;letter-spacing:.04em;}\n.ev-body img{border-radius:var(--radius-sm);border:1px solid var(--line);margin:14px 0;}\n.ev-conclusion{\n  background:var(--green-100);color:var(--green);font-weight:700;padding:14px 18px;border-radius:var(--radius-sm);\n  font-size:14.5px;margin-top:10px;\n}\n\n\/* ============ DOSING \/ MODE OF USE ============ *\/\n.dose-band{\n  background:var(--blue-900);color:#fff;border-radius:var(--radius-lg);\n  display:flex;align-items:stretch;flex-wrap:wrap;overflow:hidden;\n}\n.dose-band-photo{flex:0 0 320px;position:relative;min-height:300px;}\n.dose-band-photo img{position:absolute;inset:0;width:100%;height:100%;object-fit:cover;display:block;}\n.dose-band-content{flex:1;min-width:280px;padding:44px;display:flex;flex-direction:column;gap:24px;justify-content:center;}\n.dose-band h3{color:#fff;font-size:22px;}\n.dose-phase{display:flex;gap:14px;flex-wrap:wrap;}\n.phase-block{flex:1;min-width:130px;background:rgba(255,255,255,.08);border-radius:var(--radius-sm);padding:18px;text-align:center;}\n.phase-block b{display:block;font-family:'Fraunces',serif;font-size:26px;margin-bottom:4px;}\n.phase-block span{font-size:12.5px;color:#B9D6E4;}\n@media(max-width:700px){\n  .dose-band-photo{flex-basis:auto;width:100%;height:220px;min-height:0;}\n  .dose-band-content{padding:32px 24px;}\n}\n.indications-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:16px;margin-top:40px;}\n@media(max-width:900px){.indications-grid{grid-template-columns:repeat(2,1fr);}}\n.ind-card{\n  border:1px solid var(--line);border-radius:var(--radius-sm);padding:18px 14px;text-align:center;background:var(--paper);\n  transition:transform .3s ease, box-shadow .3s ease, border-color .3s ease;\n}\n.ind-card:hover{transform:translateY(-4px);box-shadow:var(--shadow-card);border-color:var(--blue-200);}\n.ind-card .ic{width:38px;height:38px;margin:0 auto 10px;color:var(--blue-600);}\n.ind-card span{font-size:13px;font-weight:700;color:var(--blue-900);}\n.timeline{display:flex;justify-content:space-between;margin-top:44px;position:relative;padding-top:20px;}\n.timeline::before{content:\"\";position:absolute;top:5px;left:0;right:0;height:2px;background:var(--line);}\n.tl-step{text-align:center;flex:1;position:relative;padding:0 6px;}\n.tl-step::before{content:\"\";display:block;width:11px;height:11px;border-radius:50%;background:var(--blue-600);margin:0 auto 10px;position:relative;z-index:1;}\n.tl-step span{font-size:13px;font-weight:700;color:var(--blue-900);}\n@media(max-width:640px){\n  .timeline{display:grid;grid-template-columns:1fr 1fr;gap:28px 10px;}\n  .timeline::before{display:none;}\n  .tl-step{padding:0;}\n}\n\n\/* ============ SPRAIN FLOW ============ *\/\n.flow-wrap{display:flex;flex-direction:column;align-items:center;gap:0;}\n.flow-top{\n  background:var(--blue-100);color:var(--blue-700);font-weight:700;padding:14px 26px;border-radius:999px;\n  font-size:14.5px;margin-bottom:26px;\n}\n.flow-row{display:grid;grid-template-columns:repeat(3,1fr);gap:20px;width:100%;}\n@media(max-width:800px){.flow-row{grid-template-columns:1fr;}}\n.flow-col{border:1px solid var(--line);border-radius:var(--radius-md);overflow:hidden;background:#fff;}\n.flow-col .head{padding:16px;text-align:center;font-weight:800;font-size:13.5px;letter-spacing:.03em;color:#fff;}\n.flow-col.a .head{background:var(--blue-700);}\n.flow-col.b .head{background:var(--coral);}\n.flow-col.c .head{background:var(--slate);}\n.flow-col ul{list-style:none;margin:0;padding:18px;display:flex;flex-direction:column;gap:10px;}\n.flow-col li{font-size:13.5px;color:var(--slate);text-align:center;}\n.flow-col .check{\n  display:flex;align-items:center;justify-content:center;gap:8px;padding:12px;\n  background:var(--green-100);color:var(--green);font-weight:700;font-size:13px;\n}\n.flow-col .nocheck{\n  display:flex;align-items:center;justify-content:center;padding:12px;\n  color:var(--slate-light);font-weight:600;font-size:12.5px;\n}\n\n\/* ============ PATHOLOGY TABLE ============ *\/\n.path-table{width:100%;border-collapse:collapse;font-size:14.5px;}\n.path-table th{\n  text-align:left;padding:16px 20px;background:var(--blue-900);color:#fff;font-weight:700;font-size:13px;\n  text-transform:uppercase;letter-spacing:.03em;\n}\n.path-table th:first-child{border-radius:var(--radius-sm) 0 0 0;}\n.path-table th:last-child{border-radius:0 var(--radius-sm) 0 0;}\n.path-table td{padding:16px 20px;border-bottom:1px solid var(--line);color:var(--slate);}\n.path-table tr:nth-child(even) td{background:var(--paper);}\n.path-table td:first-child{font-weight:700;color:var(--blue-900);}\n.table-scroll{overflow-x:auto;border-radius:var(--radius-md);border:1px solid var(--line);}\n\n\/* ============ QUALITY \/ CERTS ============ *\/\n.cert-grid{display:grid;grid-template-columns:repeat(4,1fr);gap:18px;}\n@media(max-width:900px){.cert-grid{grid-template-columns:repeat(2,1fr);}}\n.cert-card{\n  border:1px solid var(--line);border-radius:var(--radius-md);padding:24px;text-align:center;background:#fff;\n  transition:transform .3s ease, box-shadow .3s ease;\n}\n.cert-card:hover{transform:translateY(-5px);box-shadow:var(--shadow-card);}\n.cert-card .ic{width:40px;height:40px;margin:0 auto 14px;color:var(--blue-600);}\n.cert-card h4{font-size:14.5px;margin-bottom:6px;}\n.cert-card p{font-size:12.5px;margin:0;}\n\n\/* ============ PATENT ============ *\/\n.patent-sec{\n  background:linear-gradient(135deg,var(--blue-900) 0%, var(--blue-700) 100%);\n  color:#fff;border-radius:var(--radius-lg);padding:64px 48px;text-align:center;\n}\n.patent-sec h2{color:#fff;}\n.patent-flags{display:flex;justify-content:center;gap:18px;margin:22px 0 28px;flex-wrap:wrap;}\n.flag-chip{background:rgba(255,255,255,.12);padding:9px 18px;border-radius:999px;font-weight:700;font-size:13.5px;white-space:nowrap;}\n.patent-quote{\n  font-family:'Fraunces',serif;font-style:italic;font-size:clamp(18px,2.6vw,28px);max-width:640px;margin:0 auto;\n  color:#fff;font-weight:500;line-height:1.4;\n}\n@media(max-width:640px){\n  .patent-sec{padding:44px 22px;border-radius:var(--radius-md);}\n  .patent-sec .eyebrow{font-size:11px;}\n  .patent-sec h2{font-size:clamp(22px,6vw,30px);}\n  .patent-flags{gap:10px;}\n  .flag-chip{font-size:12px;padding:8px 14px;}\n  .patent-quote{font-size:17px;}\n}\n\n\/* ============ FAQ ============ *\/\n.faq-list{max-width:800px;margin:0 auto;display:flex;flex-direction:column;gap:12px;}\ndetails.faq{border-bottom:1px solid var(--line);padding:6px 0;}\ndetails.faq summary{\n  list-style:none;cursor:pointer;padding:16px 0;display:flex;justify-content:space-between;align-items:center;\n  font-weight:700;font-size:16px;color:var(--blue-900);gap:20px;\n}\ndetails.faq summary::-webkit-details-marker{display:none;}\ndetails.faq .ev-plus{width:26px;height:26px;font-size:16px;}\ndetails.faq p{padding:0 0 18px;font-size:14.5px;}\n\n\/* ============ FINAL CTA ============ *\/\n.final-cta{\n  position:relative;overflow:hidden;\n  background:var(--blue-600) url('https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/foto-doltendix-2.png') center\/cover no-repeat;\n  border-radius:var(--radius-lg);\n  padding:64px 48px;text-align:center;color:#fff;\n}\n.final-cta::before{\n  content:\"\";position:absolute;inset:0;z-index:0;\n  background:linear-gradient(160deg, rgba(5,42,61,.90) 0%, rgba(0,110,175,.80) 55%, rgba(0,137,204,.65) 100%);\n}\n.final-cta > *{position:relative;z-index:1;}\n.final-cta h2{color:#fff;}\n.final-cta p{color:#DCF1FC;max-width:520px;margin:0 auto 28px;}\n@media(max-width:640px){\n  .final-cta{padding:44px 22px;border-radius:var(--radius-md);}\n  .final-cta h2{font-size:clamp(22px,6vw,30px);}\n  .final-cta p{font-size:14.5px;}\n  .final-cta .btn{width:100%;max-width:320px;}\n}\n\n\/* ============ STUDY CHARTS (SVG) ============ *\/\n.dx-fig{margin:16px 0;padding:20px 18px 16px;border:1px solid var(--line);border-radius:var(--radius-sm);background:#fff;}\n.dx-fig-title{font-family:'Fraunces',serif;font-weight:600;font-size:16.5px;line-height:1.3;color:var(--blue-900);margin:0 0 14px;text-align:center;}\n.dx-fig-grid{display:grid;grid-template-columns:repeat(2,minmax(0,1fr));gap:18px 22px;align-items:end;}\n.dx-fig-grid.cols-1{grid-template-columns:minmax(0,1fr);}\n.dx-fig-grid.narrow{max-width:720px;margin:0 auto;}\n.dx-fig-panel{min-width:0;}\n.dx-fig svg{width:100%;height:auto;display:block;overflow:visible;}\n.dx-legend{display:flex;flex-wrap:wrap;gap:8px 20px;justify-content:center;margin:12px 0 0;font-size:12.5px;font-weight:600;color:var(--slate);line-height:1.4;}\n.dx-legend span{display:inline-flex;align-items:center;gap:7px;}\n.dx-legend i{display:inline-block;width:11px;height:11px;border-radius:50%;flex:none;}\n.dx-fig-note{font-size:11.5px;color:var(--slate-light);margin:12px auto 0;text-align:center;line-height:1.55;max-width:760px;}\n@media(max-width:640px){\n  .dx-fig{padding:16px 10px 12px;}\n  .dx-fig-grid{grid-template-columns:minmax(0,1fr);gap:22px;}\n  .dx-fig-grid.keep-2{grid-template-columns:repeat(2,minmax(0,1fr));gap:12px 8px;}\n}\n\n\/* reveal animation (progressive enhancement \u2014 visible by default) *\/\n.reveal{opacity:1;transform:translateY(0);transition:opacity .7s ease, transform .7s ease;}\n.js-ready .reveal{opacity:0;transform:translateY(18px);}\n.js-ready .reveal.in{opacity:1;transform:translateY(0);}\n\n\/* utils *\/\n.text-center{text-align:center;}\n.mt-40{margin-top:40px;}\n.grid-2{display:grid;grid-template-columns:1fr 1fr;gap:24px;}\n@media(max-width:800px){.grid-2{grid-template-columns:1fr;}}\n<\/style>\n\n\n\n<!-- ============ HERO ============ -->\n<section class=\"hero\" id=\"top\">\n  <div class=\"lang-switch\">\n    <a href=\"https:\/\/order-science.com\/doltendix\/\">ES<\/a>\n    <span class=\"active\">EN<\/span>\n  <\/div>\n  <div class=\"hero-grid\">\n    <div class=\"reveal in\">\n      <div class=\"eyebrow\">Kolinpharma\u00ae \u00b7 Leader to Health<\/div>\n      <h1>Specialized nutrition for <em>tendons and ligaments<\/em>.<\/h1>\n      <p class=\"hero-sub\">Doltendix\u00ae combines tendon-specific bioactive collagen peptides, astaxanthin, trans-resveratrol and vitamin C: a nutritional supplement formula developed with selected ingredients backed by scientific research. The highest dose of specific collagen available on the market.<\/p>\n      <div class=\"hero-ctas buy-row\">\n        <div class=\"qty-selector\" role=\"group\" aria-label=\"Quantity\">\n          <button type=\"button\" class=\"qty-btn qty-minus\" aria-label=\"Decrease quantity\">\u2212<\/button>\n          <input type=\"number\" class=\"qty-input\" value=\"1\" min=\"1\" max=\"99\" inputmode=\"numeric\" aria-label=\"Quantity\">\n          <button type=\"button\" class=\"qty-btn qty-plus\" aria-label=\"Increase quantity\">+<\/button>\n        <\/div>\n        <a href=\"https:\/\/order-science.com\/checkout\/?add-to-cart=400&amp;quantity=1\" class=\"btn btn-primary btn-buy doltendix-buy-link\" data-base-url=\"https:\/\/order-science.com\/checkout\/?add-to-cart=400\" data-product-id=\"400\" target=\"_blank\" rel=\"noopener\">\n          <span class=\"cta-label\">Add to cart<\/span>\n          <span class=\"cta-price\">$75.000<\/span>\n        <\/a>\n        <a href=\"#mecanismo\" class=\"btn btn-ghost\">Discover the formula<\/a>\n      <\/div>\n      <div class=\"badge-row\">\n        <span class=\"badge\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"><path d=\"M12 2l2.4 6.6L21 11l-6.6 2.4L12 20l-2.4-6.6L3 11l6.6-2.4z\"><\/path><\/svg>Patented in Italy and China<\/span>\n        <span class=\"badge\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"><path d=\"M9 12l2 2 4-4\"><\/path><circle cx=\"12\" cy=\"12\" r=\"9\"><\/circle><\/svg>Ingredients with published research<\/span>\n        <span class=\"badge\"><svg viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"2\"><path d=\"M12 2l7 4v6c0 5-3.5 8-7 10-3.5-2-7-5-7-10V6z\"><\/path><\/svg>ISO 9001 \u00b7 14001 \u00b7 22000<\/span>\n      <\/div>\n    <\/div>\n    <div class=\"hero-visual reveal in\">\n      <img decoding=\"async\" class=\"hero-photo\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/doltendix-img.jpg\" alt=\"Person holding their knee \u2014 Doltendix for tendons and ligaments\">\n      <img decoding=\"async\" class=\"hero-product-img\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/box.png\" alt=\"Doltendix \u2014 product box, 20 sachets of 5 g\">\n    <\/div>\n  <\/div>\n\n  <div class=\"hero-strip\">\n    <div class=\"stat-row\">\n      <div class=\"stat-cell\"><div class=\"stat-num\"><span class=\"countup\" data-target=\"5000\">0<\/span> mg<\/div><div class=\"stat-label\">TENDOFORTE\u00ae collagen<\/div><\/div>\n      <div class=\"stat-cell\"><div class=\"stat-num\"><span class=\"countup\" data-target=\"8\">0<\/span> mg<\/div><div class=\"stat-label\">AstaReal\u00ae astaxanthin<\/div><\/div>\n      <div class=\"stat-cell\"><div class=\"stat-num\"><span class=\"countup\" data-target=\"500\">0<\/span> mg<\/div><div class=\"stat-label\">Vitamin C (625% NRV)<\/div><\/div>\n      <div class=\"stat-cell\"><div class=\"stat-num\"><span class=\"countup\" data-target=\"150\">0<\/span> mg<\/div><div class=\"stat-label\">Veri\u00b7Sperse\u00ae trans-resveratrol<\/div><\/div>\n      <div class=\"stat-cell\"><div class=\"stat-num\"><span class=\"countup\" data-target=\"20\">0<\/span><\/div><div class=\"stat-label\">5 g sachets per box<\/div><\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ CLOSE-UP GALLERY ============ -->\n<section class=\"section-pad\" id=\"producto\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">The product<\/div>\n      <h2>Every detail, <em>up close<\/em><\/h2>\n      <p>A powdered dietary supplement in single-dose sachets, easy to measure and add to your daily routine.<\/p>\n    <\/div>\n    <div class=\"gallery-grid\">\n      <div class=\"gallery-card reveal\">\n        <div class=\"imgwrap\"><img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/box.png\" alt=\"Doltendix box\"><\/div>\n        <div class=\"cap\">Box of 20 sachets of 5 g<\/div>\n      <\/div>\n      <div class=\"gallery-card reveal\">\n        <div class=\"imgwrap\"><img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/sachet-alone.png\" alt=\"Single Doltendix sachet\" style=\"max-height:260px;\"><\/div>\n        <div class=\"cap\">Single-dose sachet, with sweetener<\/div>\n      <\/div>\n      <div class=\"gallery-card reveal\">\n        <div class=\"imgwrap\" style=\"background:var(--blue-900);\">\n          <div style=\"color:#fff;text-align:left;width:100%;\">\n            <div style=\"font-family:'Fraunces',serif;font-size:15px;color:#B9D6E4;margin-bottom:14px;\">Composition per daily dose (2 sachets)<\/div>\n            <div style=\"display:flex;flex-direction:column;gap:10px;\">\n              <div style=\"display:flex;justify-content:space-between;border-bottom:1px solid rgba(255,255,255,.15);padding-bottom:8px;\"><span style=\"font-size:13px;\">TENDOFORTE\u00ae collagen<\/span><b style=\"color:var(--blue-500);\">5000 mg<\/b><\/div>\n              <div style=\"display:flex;justify-content:space-between;border-bottom:1px solid rgba(255,255,255,.15);padding-bottom:8px;\"><span style=\"font-size:13px;\">AstaReal\u00ae astaxanthin<\/span><b style=\"color:var(--blue-500);\">8 mg<\/b><\/div>\n              <div style=\"display:flex;justify-content:space-between;border-bottom:1px solid rgba(255,255,255,.15);padding-bottom:8px;\"><span style=\"font-size:13px;\">Vitamin C<\/span><b style=\"color:var(--blue-500);\">500 mg<\/b><\/div>\n              <div style=\"display:flex;justify-content:space-between;\"><span style=\"font-size:13px;\">Veri\u00b7Sperse\u00ae trans-resveratrol<\/span><b style=\"color:var(--blue-500);\">150 mg<\/b><\/div>\n            <\/div>\n          <\/div>\n        <\/div>\n        <div class=\"cap\">Nutrition facts \u2014 EU Reg. 1169\/2011<\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ PROBLEM \/ SYMPTOMS ============ -->\n<section class=\"section-pad problem-sec\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\" style=\"color:var(--blue-500);\">Who it is for<\/div>\n      <h2>Nutrition and care for <em>tendons and ligaments<\/em><\/h2>\n      <p>Designed for people who want to complement their daily diet with bioactive collagen peptides, in routines with high physical demands and everyday movement.<\/p>\n    <\/div>\n    <div class=\"problem-grid\">\n      <div class=\"problem-photos reveal\">\n        <figure><img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/dolor-1.png\" alt=\"Active person training\"><\/figure>\n        <figure><img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/dolor-2.png\" alt=\"Active person in motion\"><\/figure>\n      <\/div>\n      <div class=\"reveal\" style=\"padding:0 0 0 20px;\">\n        <div class=\"symptom-list\">\n          <div class=\"symptom-item\"><span class=\"dot\"><\/span>Physical and sports demands<\/div>\n          <div class=\"symptom-item\"><span class=\"dot\"><\/span>Everyday activity and movement<\/div>\n          <div class=\"symptom-item\"><span class=\"dot\"><\/span>Demanding training routines<\/div>\n          <div class=\"symptom-item\"><span class=\"dot\"><\/span>Active lifestyle<\/div>\n          <div class=\"symptom-item\"><span class=\"dot\"><\/span>Need to complement daily nutrition<\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ MECHANISM ============ -->\n<section class=\"section-pad\" id=\"mecanismo\">\n  <div class=\"container\">\n    <div class=\"section-head center reveal\" style=\"margin-left:auto;margin-right:auto;\">\n      <div class=\"eyebrow\">The formula<\/div>\n      <h2>Developed with nutrients and <em>selected ingredients<\/em><\/h2>\n    <\/div>\n\n    <div class=\"mech-grid reveal\">\n      <div>\n        <div class=\"cycle-wrap\">\n          <div class=\"cycle-ring\"><\/div>\n          <div class=\"cycle-node n1\">Specific collagen<\/div>\n          <div class=\"cycle-node n2\">Tendon and ligament structure<\/div>\n          <div class=\"cycle-node n3\">Antioxidants<\/div>\n          <div class=\"cycle-center\">\n            <img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/logo.png\" alt=\"\" style=\"height:20px;object-fit:contain;\">\n            <b>4 actives<\/b>\n            <span>in one formula<\/span>\n          <\/div>\n        <\/div>\n      <\/div>\n      <div>\n        <span class=\"tag\" style=\"background:var(--blue-100);\">The formulation<\/span>\n        <h3>A combination of selected ingredients<\/h3>\n        <p>Doltendix\u00ae was developed with a specific combination of bioactive collagen peptides and selected micronutrients, brought together in a single daily dose to complement the nutrition of tendons and ligaments.<\/p>\n      <\/div>\n    <\/div>\n\n    <div class=\"mech-grid reveal\" style=\"margin-top:80px;\">\n      <div>\n        <span class=\"tag\" style=\"background:var(--coral-100);color:var(--coral);\">Scientific evidence<\/span>\n        <h3>Studied in experimental models<\/h3>\n        <p>In an in vitro study on human tenocytes (tendon cells), the formulation was evaluated against different biomarkers associated with inflammatory processes (IL-1\u03b2) and oxidative stress (reactive oxygen species, ROS).<\/p>\n        <p style=\"font-size:12.5px;color:var(--slate-light);\">Source: <em>Mediators of Inflammation<\/em>, Impact Factor 4.4 \u2014 2024 Jul 30:2024:5273198. doi: 10.1155\/2024\/5273198.<\/p>\n      <\/div>\n      <div class=\"action-card\">\n        <div style=\"font-size:13px;font-weight:700;color:var(--slate);text-align:center;margin-bottom:6px;\">In vitro study \u2014 human tenocytes<\/div>\n        <div class=\"stop-diagram\">\n          <div class=\"stop-pill\"><div class=\"circle\">IL-1\u03b2<\/div>Inflammatory marker<\/div>\n          <div class=\"stop-center\">STUDY<\/div>\n          <div class=\"stop-pill\"><div class=\"circle\">ROS<\/div>Oxidative stress<\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ WHY CHOOSE ============ -->\n<section class=\"section-pad\" style=\"background:var(--paper);\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">Why choose Doltendix<\/div>\n      <h2>For tendons and <em>ligaments<\/em><\/h2>\n    <\/div>\n    <div class=\"why-grid\">\n      <div class=\"why-card reveal\">\n        <span class=\"tag\">Composition<\/span>\n        <h3>Research on specific collagen<\/h3>\n        <p>The formula\u2019s bioactive collagen peptides were studied in relation to the collagen composition of tendons and ligaments, in research models.<\/p>\n        <div class=\"before-after\">\n          <div class=\"ba-col before\"><b>Model<\/b><span>Type III collagen \u2014 \u201crigid structure\u201d<\/span><\/div>\n          <div class=\"ba-col after\"><b>Research<\/b><span>Type I collagen \u2014 \u201celastic structure\u201d<\/span><\/div>\n        <\/div>\n      <\/div>\n      <div class=\"why-card reveal\">\n        <span class=\"tag\">The highest dose<\/span>\n        <h3>Of specific collagen (bioactive peptides) available on the market<\/h3>\n        <p>With 5000 mg of TENDOFORTE\u00ae collagen per daily dose, Doltendix\u00ae far exceeds the concentration of other comparable supplements on the market.<\/p>\n        <img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/dose-comparison-chart.png\" alt=\"Comparison of specific collagen dose in mg: Doltendix versus other products on the market (A-E)\">\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ COMPOSITION ============ -->\n<section class=\"section-pad\" id=\"composicion\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">Composition<\/div>\n      <h2>Four actives, <em>one synergy<\/em><\/h2>\n      <p>Each Doltendix\u00ae ingredient has a specific role and its own scientific backing, brought together in a single formula with published research on tendons and ligaments.<\/p>\n    <\/div>\n    <div class=\"comp-grid\">\n      <div class=\"comp-card reveal\">\n        <div class=\"comp-icon\">\n          <svg width=\"22\" height=\"22\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\"><path d=\"M4 4c4 0 4 4 8 4s4-4 8-4M4 12c4 0 4 4 8 4s4-4 8-4M4 20c4 0 4 4 8 4s4-4 8-4\"><\/path><\/svg>\n        <\/div>\n        <div class=\"dose\">5000 mg<\/div>\n        <h4>Bioactive collagen peptides<\/h4>\n        <div class=\"sub\">TENDOFORTE\u00ae<\/div>\n        <ul>\n          <li>High absorption and bioavailability<\/li>\n          <li>High tendon specificity (optimal molecular weight of 2000 g\/mol)<\/li>\n          <li>Studied in research for their relationship with type I collagen synthesis<\/li>\n        <\/ul>\n      <\/div>\n      <div class=\"comp-card reveal\">\n        <div class=\"comp-icon\">\n          <svg width=\"22\" height=\"22\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\"><circle cx=\"12\" cy=\"12\" r=\"4\"><\/circle><path d=\"M12 2v3M12 19v3M2 12h3M19 12h3M4.9 4.9l2.1 2.1M17 17l2.1 2.1M4.9 19.1L7 17M17 7l2.1-2.1\"><\/path><\/svg>\n        <\/div>\n        <div class=\"dose\">8 mg<\/div>\n        <h4>Astaxanthin<\/h4>\n        <div class=\"sub\">AstaReal\u00ae<\/div>\n        <ul>\n          <li>Studied for its activity on macrophages in scientific research<\/li>\n          <li>Evaluated in relation to type I\/III collagen in preclinical models<\/li>\n          <li>Studied in preclinical models of tendon tensile strength<\/li>\n        <\/ul>\n      <\/div>\n      <div class=\"comp-card reveal\">\n        <div class=\"comp-icon\">\n          <svg width=\"22\" height=\"22\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\"><path d=\"M12 2v20M4 8l8-6 8 6M6 20h12\"><\/path><\/svg>\n        <\/div>\n        <div class=\"dose\">150 mg<\/div>\n        <h4>Trans-resveratrol<\/h4>\n        <div class=\"sub\">Veri\u00b7Sperse\u00ae<\/div>\n        <ul>\n          <li>Studied on human tenocytes in in vitro research<\/li>\n          <li>Evaluated for its relationship with microcirculation in experimental studies<\/li>\n          <li>3 times the bioavailability of standard trans-resveratrol<\/li>\n        <\/ul>\n      <\/div>\n      <div class=\"comp-card reveal\">\n        <div class=\"comp-icon\">\n          <svg width=\"22\" height=\"22\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.8\"><path d=\"M12 3l1.9 5.8H20l-4.9 3.6 1.9 5.8L12 14.6l-4.9 3.6 1.9-5.8L4 8.8h6.1z\"><\/path><\/svg>\n        <\/div>\n        <div class=\"dose\">500 mg<\/div>\n        <h4>Vitamin C<\/h4>\n        <div class=\"sub\">625% NRV<\/div>\n        <ul>\n          <li>Contributes to normal collagen formation*<\/li>\n          <li>Studied in relation to tissue repair processes in experimental research<\/li>\n          <li>Evaluated in experimental models of connective tissue<\/li>\n        <\/ul>\n        <p style=\"font-size:11px;color:var(--slate-light);margin:10px 0 0;\">*Health claim subject to verification of current authorization by ANMAT.<\/p>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ EVIDENCE ============ -->\n<section class=\"section-pad\" style=\"background:var(--paper);\" id=\"evidencia\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">The scientific basis<\/div>\n      <h2>Clinical and <em>preclinical evidence<\/em><\/h2>\n      <p>The results of Doltendix\u00ae and each of its actives are backed by in vitro, preclinical and clinical studies.<\/p>\n    <\/div>\n\n    <div class=\"evidence-list reveal\">\n\n      <details class=\"ev-item\" open=\"\">\n        <summary>In vitro study \u2014 full Doltendix\u00ae formula<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">Human tenocytes \u00b7 Anti-inflammatory and antioxidant properties of a new mixture of vitamin C, collagen peptides, resveratrol and astaxanthin in tenocytes<\/div>\n          <p>In the in vitro study, the combination of vitamin C, collagen peptides, trans-resveratrol and astaxanthin showed differences compared with each active substance evaluated separately, with a significant reduction of IL-6 and MMP-2 in the cell model.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Anti-inflammatory action \u00b7 in vitro study on human tenocytes<\/div><div class=\"dx-fig-grid cols-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"IL-6\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >IL-6<\/text><line x1=\"62\" y1=\"302.0\" x2=\"464\" y2=\"302.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"306.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.0<\/text><line x1=\"62\" y1=\"238.0\" x2=\"464\" y2=\"238.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"242.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.5<\/text><line x1=\"62\" y1=\"174.0\" x2=\"464\" y2=\"174.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"178.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.0<\/text><line x1=\"62\" y1=\"110.0\" x2=\"464\" y2=\"110.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"114.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.5<\/text><line x1=\"62\" y1=\"302\" x2=\"464\" y2=\"302\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"206.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 206.0)\">IL-6 (fold change vs IL-1\u03b2)<\/text><rect x=\"74.7\" y=\"174.0\" width=\"41.5\" height=\"128.0\" rx=\"3\" fill=\"#052A3D\"\/><path d=\"M95.5 168.9V174.0M88.5 168.9H102.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"95.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >IL-1\u03b2<\/text><rect x=\"141.7\" y=\"184.2\" width=\"41.5\" height=\"117.8\" rx=\"3\" fill=\"#5BB3DD\"\/><path d=\"M162.5 176.6V184.2M155.5 176.6H169.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"162.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Vit C<\/text><rect x=\"208.7\" y=\"211.1\" width=\"41.5\" height=\"90.9\" rx=\"3\" fill=\"#075D86\"\/><path d=\"M229.5 200.9V211.1M222.5 200.9H236.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"229.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Coll<\/text><rect x=\"275.7\" y=\"185.5\" width=\"41.5\" height=\"116.5\" rx=\"3\" fill=\"#1596D6\"\/><path d=\"M296.5 181.7V185.5M289.5 181.7H303.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"296.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Resv<\/text><rect x=\"342.7\" y=\"197.0\" width=\"41.5\" height=\"105.0\" rx=\"3\" fill=\"#BFE4F6\"\/><path d=\"M363.5 194.5V197.0M356.5 194.5H370.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"363.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Asx<\/text><rect x=\"409.7\" y=\"273.8\" width=\"41.5\" height=\"28.2\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M430.5 258.5V273.8M423.5 258.5H437.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"430.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"700\" >Doltendix\u00ae<\/text><path d=\"M95.5 163.9V158.9H229.5V195.9\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"162.5\" y=\"154.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><path d=\"M95.5 163.9V138.9H363.5V189.5\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"229.5\" y=\"134.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">**<\/text><path d=\"M95.5 163.9V118.9H430.5V253.5\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"263.0\" y=\"114.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">****<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"MMP-2\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >MMP-2<\/text><line x1=\"62\" y1=\"302.0\" x2=\"464\" y2=\"302.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"306.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"195.0\" x2=\"464\" y2=\"195.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"199.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1<\/text><line x1=\"62\" y1=\"88.0\" x2=\"464\" y2=\"88.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"92.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2<\/text><line x1=\"62\" y1=\"302\" x2=\"464\" y2=\"302\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"195.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 195.0)\">MMP-2 (fold change vs IL-1\u03b2)<\/text><rect x=\"74.7\" y=\"195.0\" width=\"41.5\" height=\"107.0\" rx=\"3\" fill=\"#052A3D\"\/><path d=\"M95.5 186.4V195.0M88.5 186.4H102.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"95.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >IL-1\u03b2<\/text><rect x=\"141.7\" y=\"136.2\" width=\"41.5\" height=\"165.8\" rx=\"3\" fill=\"#5BB3DD\"\/><path d=\"M162.5 127.6V136.2M155.5 127.6H169.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"162.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Vit C<\/text><rect x=\"208.7\" y=\"189.6\" width=\"41.5\" height=\"112.4\" rx=\"3\" fill=\"#075D86\"\/><path d=\"M229.5 181.1V189.6M222.5 181.1H236.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"229.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Coll<\/text><rect x=\"275.7\" y=\"166.1\" width=\"41.5\" height=\"135.9\" rx=\"3\" fill=\"#1596D6\"\/><path d=\"M296.5 161.8V166.1M289.5 161.8H303.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"296.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Resv<\/text><rect x=\"342.7\" y=\"197.1\" width=\"41.5\" height=\"104.9\" rx=\"3\" fill=\"#BFE4F6\"\/><path d=\"M363.5 192.9V197.1M356.5 192.9H370.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"363.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Asx<\/text><rect x=\"409.7\" y=\"234.6\" width=\"41.5\" height=\"67.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M430.5 223.9V234.6M423.5 223.9H437.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"430.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"700\" >Doltendix\u00ae<\/text><path d=\"M95.5 181.4V117.6H162.5V122.6\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"129.0\" y=\"113.6\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">****<\/text><path d=\"M95.5 181.4V97.6H430.5V218.9\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"263.0\" y=\"93.6\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><\/svg><\/div><\/div><div class=\"dx-fig-note\">IL-1\u03b2: cells stimulated with IL-1\u03b2 (control) \u00b7 Vit C: vitamin C \u00b7 Coll: collagen peptides \u00b7 Resv: trans-resveratrol \u00b7 Asx: astaxanthin \u2014 *p&lt;0.05 \u00b7 **p&lt;0.01 \u00b7 ***p&lt;0.001 \u00b7 ****p&lt;0.0001<\/div><\/figure>\n          <p style=\"margin-top:18px;\">The same study also recorded a significant reduction of reactive oxygen species (ROS) in the cell model.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Antioxidant action \u00b7 in vitro study on human tenocytes<\/div><div class=\"dx-fig-grid cols-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"ROS vs control\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >ROS vs control<\/text><line x1=\"62\" y1=\"296.0\" x2=\"464\" y2=\"296.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"300.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"238.5\" x2=\"464\" y2=\"238.5\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"242.5\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1<\/text><line x1=\"62\" y1=\"181.0\" x2=\"464\" y2=\"181.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"185.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2<\/text><line x1=\"62\" y1=\"123.5\" x2=\"464\" y2=\"123.5\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"127.5\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >3<\/text><line x1=\"62\" y1=\"66.0\" x2=\"464\" y2=\"66.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"70.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4<\/text><line x1=\"62\" y1=\"296\" x2=\"464\" y2=\"296\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"181.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 181.0)\">ROS (fold induction vs control)<\/text><rect x=\"81.1\" y=\"238.5\" width=\"62.3\" height=\"57.5\" rx=\"3\" fill=\"#052A3D\"\/><path d=\"M112.2 224.1V238.5M105.2 224.1H119.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"112.2\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Control<\/text><rect x=\"181.6\" y=\"123.5\" width=\"62.3\" height=\"172.5\" rx=\"3\" fill=\"#5BB3DD\"\/><path d=\"M212.8 86.1V123.5M205.8 86.1H219.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"212.8\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >H\u2082O\u2082<\/text><rect x=\"282.1\" y=\"223.0\" width=\"62.3\" height=\"73.0\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M313.2 212.6V223.0M306.2 212.6H320.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"313.2\" y=\"314.0\" font-size=\"12.5\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"700\" >Doltendix\u00ae<\/text><rect x=\"382.6\" y=\"185.6\" width=\"62.3\" height=\"110.4\" rx=\"3\" fill=\"#29ABE8\"\/><path d=\"M413.8 170.1V185.6M406.8 170.1H420.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"413.8\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >H\u2082O\u2082 +<\/text><text x=\"413.8\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >Doltendix\u00ae<\/text><path d=\"M212.8 81.1V76.1H413.8V165.1\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"313.2\" y=\"72.1\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"ROS vs H\u2082O\u2082\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >ROS vs H\u2082O\u2082<\/text><line x1=\"62\" y1=\"296.0\" x2=\"464\" y2=\"296.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"300.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.0<\/text><line x1=\"62\" y1=\"241.3\" x2=\"464\" y2=\"241.3\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"245.3\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.5<\/text><line x1=\"62\" y1=\"186.7\" x2=\"464\" y2=\"186.7\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"190.7\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.0<\/text><line x1=\"62\" y1=\"132.0\" x2=\"464\" y2=\"132.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"136.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.5<\/text><line x1=\"62\" y1=\"296\" x2=\"464\" y2=\"296\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"214.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 214.0)\">ROS (fold induction vs H\u2082O\u2082)<\/text><rect x=\"74.7\" y=\"186.7\" width=\"41.5\" height=\"109.3\" rx=\"3\" fill=\"#052A3D\"\/><path d=\"M95.5 177.9V186.7M88.5 177.9H102.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"95.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >H\u2082O\u2082<\/text><rect x=\"141.7\" y=\"208.5\" width=\"41.5\" height=\"87.5\" rx=\"3\" fill=\"#5BB3DD\"\/><path d=\"M162.5 192.1V208.5M155.5 192.1H169.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"162.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Vit C<\/text><rect x=\"208.7\" y=\"184.5\" width=\"41.5\" height=\"111.5\" rx=\"3\" fill=\"#075D86\"\/><path d=\"M229.5 175.7V184.5M222.5 175.7H236.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"229.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Coll<\/text><rect x=\"275.7\" y=\"228.2\" width=\"41.5\" height=\"67.8\" rx=\"3\" fill=\"#1596D6\"\/><path d=\"M296.5 220.6V228.2M289.5 220.6H303.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"296.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Resv<\/text><rect x=\"342.7\" y=\"214.0\" width=\"41.5\" height=\"82.0\" rx=\"3\" fill=\"#BFE4F6\"\/><path d=\"M363.5 209.6V214.0M356.5 209.6H370.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"363.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Asx<\/text><rect x=\"409.7\" y=\"233.7\" width=\"41.5\" height=\"62.3\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M430.5 219.5V233.7M423.5 219.5H437.5\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"430.5\" y=\"314.0\" font-size=\"12.5\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"700\" >Doltendix\u00ae<\/text><path d=\"M95.5 172.9V165.7H162.5V187.1\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"129.0\" y=\"161.7\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M95.5 172.9V145.7H296.5V215.6\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"196.0\" y=\"141.7\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><path d=\"M95.5 172.9V125.7H363.5V204.6\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"229.5\" y=\"121.7\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M95.5 172.9V105.7H430.5V214.5\" stroke=\"#7C8D9B\" stroke-width=\"1.1\" fill=\"none\"\/><text x=\"263.0\" y=\"101.7\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><\/svg><\/div><\/div><div class=\"dx-fig-note\">*p&lt;0.05 \u00b7 **p&lt;0.01 \u00b7 ***p&lt;0.001 \u00b7 ****p&lt;0.0001<\/div><\/figure>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>Real-life study \u2014 150 patients with epicondylitis<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">150 patients \u00b7 2 sachets\/day for 10 days, 1 sachet\/day for 20 days<\/div>\n          <p>Participants were assessed with the VAS scale (pain) and the Quick-DASH index (disability), comparing baseline values with those recorded at the 30-day follow-up.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Real-life study \u00b7 150 patients with epicondylitis<\/div><div class=\"dx-fig-grid cols-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"Pain\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Pain<\/text><line x1=\"62\" y1=\"296.0\" x2=\"464\" y2=\"296.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"300.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"233.0\" x2=\"464\" y2=\"233.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"237.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2<\/text><line x1=\"62\" y1=\"170.0\" x2=\"464\" y2=\"170.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"174.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4<\/text><line x1=\"62\" y1=\"107.0\" x2=\"464\" y2=\"107.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"111.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >6<\/text><line x1=\"62\" y1=\"44.0\" x2=\"464\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >8<\/text><line x1=\"62\" y1=\"296\" x2=\"464\" y2=\"296\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"170.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 170.0)\">VAS (10 cm)<\/text><rect x=\"87.5\" y=\"94.4\" width=\"83.1\" height=\"201.6\" rx=\"3\" fill=\"#075D86\"\/><path d=\"M129.0 83.4V94.4M122.0 83.4H136.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"129.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Before intake<\/text><text x=\"129.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T0<\/text><rect x=\"221.5\" y=\"154.2\" width=\"83.1\" height=\"141.8\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M263.0 144.8V154.2M256.0 144.8H270.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"263.0\" y=\"138.8\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"263.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >After 10 days<\/text><text x=\"263.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T1<\/text><rect x=\"355.5\" y=\"223.6\" width=\"83.1\" height=\"72.4\" rx=\"3\" fill=\"#29ABE8\"\/><path d=\"M397.0 215.7V223.6M390.0 215.7H404.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"397.0\" y=\"209.7\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*** ###<\/text><text x=\"397.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >After 30 days<\/text><text x=\"397.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T2<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"Disability index\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Disability index<\/text><line x1=\"62\" y1=\"296.0\" x2=\"464\" y2=\"296.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"300.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"212.0\" x2=\"464\" y2=\"212.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"216.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >20<\/text><line x1=\"62\" y1=\"128.0\" x2=\"464\" y2=\"128.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"132.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >40<\/text><line x1=\"62\" y1=\"44.0\" x2=\"464\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >60<\/text><line x1=\"62\" y1=\"296\" x2=\"464\" y2=\"296\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"170.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 170.0)\">Quick-DASH (%)<\/text><rect x=\"87.5\" y=\"77.6\" width=\"83.1\" height=\"218.4\" rx=\"3\" fill=\"#075D86\"\/><path d=\"M129.0 62.9V77.6M122.0 62.9H136.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"129.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Before intake<\/text><text x=\"129.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T0<\/text><rect x=\"221.5\" y=\"140.6\" width=\"83.1\" height=\"155.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M263.0 130.1V140.6M256.0 130.1H270.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"263.0\" y=\"124.1\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"263.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >After 10 days<\/text><text x=\"263.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T1<\/text><rect x=\"355.5\" y=\"220.4\" width=\"83.1\" height=\"75.6\" rx=\"3\" fill=\"#29ABE8\"\/><path d=\"M397.0 212.0V220.4M390.0 212.0H404.0\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"397.0\" y=\"206.0\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*** ###<\/text><text x=\"397.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >After 30 days<\/text><text x=\"397.0\" y=\"329.0\" font-size=\"12.0\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >T2<\/text><\/svg><\/div><\/div><div class=\"dx-fig-note\">Regimen: 2 sachets\/day for 10 days and 1 sachet\/day for 20 days.<\/div><\/figure>\n          <div class=\"ev-conclusion\">Full results available in the corresponding scientific publication.<\/div>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>Combination with physiotherapy<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">QuickDash score over time \u2014 Doltendix\u00ae alone vs. combined with physiotherapy<\/div>\n          <p>The study evaluated the QuickDash score over time in two groups: one taking the Doltendix\u00ae formulation alone and another combining it with physiotherapy.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">QuickDash score \u00b7 Doltendix\u00ae with and without physiotherapy<\/div><div class=\"dx-fig-grid cols-1 narrow\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 720 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><line x1=\"62\" y1=\"310.0\" x2=\"704\" y2=\"310.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"272.0\" x2=\"704\" y2=\"272.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"276.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >10<\/text><line x1=\"62\" y1=\"234.0\" x2=\"704\" y2=\"234.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"238.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >20<\/text><line x1=\"62\" y1=\"196.0\" x2=\"704\" y2=\"196.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"200.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >30<\/text><line x1=\"62\" y1=\"158.0\" x2=\"704\" y2=\"158.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"162.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >40<\/text><line x1=\"62\" y1=\"120.0\" x2=\"704\" y2=\"120.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"124.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >50<\/text><line x1=\"62\" y1=\"82.0\" x2=\"704\" y2=\"82.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"86.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >60<\/text><line x1=\"62\" y1=\"44.0\" x2=\"704\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >70<\/text><line x1=\"62\" y1=\"310\" x2=\"704\" y2=\"310\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"177.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 177.0)\">QuickDash score<\/text><rect x=\"94.2\" y=\"93.4\" width=\"72.8\" height=\"216.6\" rx=\"3\" fill=\"#B9504A\"\/><path d=\"M130.6 78.2V108.6M124.6 78.2H136.6\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"171.0\" y=\"127.6\" width=\"72.8\" height=\"182.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M207.4 114.3V140.9M201.4 114.3H213.4\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"169.0\" y=\"328.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T0<\/text><rect x=\"308.2\" y=\"152.3\" width=\"72.8\" height=\"157.7\" rx=\"3\" fill=\"#B9504A\"\/><path d=\"M344.6 131.4V173.2M338.6 131.4H350.6\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"385.0\" y=\"184.6\" width=\"72.8\" height=\"125.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M421.4 173.2V196.0M415.4 173.2H427.4\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"383.0\" y=\"328.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T1<\/text><rect x=\"522.2\" y=\"232.1\" width=\"72.8\" height=\"77.9\" rx=\"3\" fill=\"#B9504A\"\/><path d=\"M558.6 215.0V249.2M552.6 215.0H564.6\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"599.0\" y=\"235.9\" width=\"72.8\" height=\"74.1\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M635.4 220.7V251.1M629.4 220.7H641.4\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"597.0\" y=\"328.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T2<\/text><\/svg><\/div><\/div><div class=\"dx-legend\"><span><i style=\"background:#B9504A\"><\/i>Doltendix\u00ae + physiotherapy (65%)<\/span><span><i style=\"background:#0089CC\"><\/i>Doltendix\u00ae alone (35%)<\/span><\/div><\/figure>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>TENDOFORTE\u00ae \u2014 athletes with Achilles tendinopathy<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">20 athletes \u00b7 Double-blind, randomized, placebo-controlled clinical study \u00b7 Journal of Sports Science and Medicine, 2018<\/div>\n          <p>Both groups performed eccentric exercises throughout the study. The group that received Tendoforte\u00ae showed differences compared with the group that performed eccentric exercises only, according to the scales assessed in the research protocol, both during the study and at the 3-month follow-up.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">TENDOFORTE\u00ae \u00b7 athletes with Achilles tendinopathy<\/div><div class=\"dx-fig-grid cols-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"VISA-A\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >VISA-A<\/text><line x1=\"62\" y1=\"280.6\" x2=\"464\" y2=\"280.6\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"284.6\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >40<\/text><line x1=\"62\" y1=\"237.7\" x2=\"464\" y2=\"237.7\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"241.7\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >60<\/text><line x1=\"62\" y1=\"194.9\" x2=\"464\" y2=\"194.9\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"198.9\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >80<\/text><line x1=\"62\" y1=\"152.0\" x2=\"464\" y2=\"152.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"156.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >100<\/text><line x1=\"62\" y1=\"302\" x2=\"464\" y2=\"302\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"227.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 227.0)\">VISA-A<\/text><rect x=\"81.4\" y=\"237.7\" width=\"45.6\" height=\"64.3\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M104.2 194.9V278.4M98.2 194.9H110.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"131.0\" y=\"233.4\" width=\"45.6\" height=\"68.6\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M153.8 182.0V282.7M147.8 182.0H159.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"129.0\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T1<\/text><text x=\"129.0\" y=\"335.0\" font-size=\"11.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >baseline<\/text><rect x=\"215.4\" y=\"209.9\" width=\"45.6\" height=\"92.1\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M238.2 169.1V248.4M232.2 169.1H244.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"265.0\" y=\"222.7\" width=\"45.6\" height=\"79.3\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M287.8 179.9V265.6M281.8 179.9H293.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"263.0\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T2<\/text><text x=\"263.0\" y=\"335.0\" font-size=\"11.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >3 months<\/text><rect x=\"349.4\" y=\"194.9\" width=\"45.6\" height=\"107.1\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M372.2 164.9V224.9M366.2 164.9H378.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"399.0\" y=\"189.5\" width=\"45.6\" height=\"112.5\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M421.8 169.1V209.9M415.8 169.1H427.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"397.0\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T3<\/text><text x=\"397.0\" y=\"335.0\" font-size=\"11.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >6 months<\/text><path d=\"M104.2 160.9V154.9H238.2V160.9\" stroke=\"#0089CC\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"171.2\" y=\"151.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M238.2 142.9V136.9H372.2V142.9\" stroke=\"#0089CC\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"305.2\" y=\"133.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M104.2 124.9V118.9H372.2V124.9\" stroke=\"#0089CC\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"238.2\" y=\"115.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M153.8 106.9V100.9H287.8V106.9\" stroke=\"#7C8D9B\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"220.8\" y=\"97.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M287.8 88.9V82.9H421.8V88.9\" stroke=\"#7C8D9B\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"354.8\" y=\"79.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><path d=\"M153.8 70.9V64.9H421.8V70.9\" stroke=\"#7C8D9B\" stroke-width=\"1.2\" fill=\"none\"\/><text x=\"287.8\" y=\"61.9\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"Return to running\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Return to running<\/text><line x1=\"62\" y1=\"302.0\" x2=\"464\" y2=\"302.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"306.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"250.4\" x2=\"464\" y2=\"250.4\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"254.4\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2<\/text><line x1=\"62\" y1=\"198.8\" x2=\"464\" y2=\"198.8\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"202.8\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4<\/text><line x1=\"62\" y1=\"147.2\" x2=\"464\" y2=\"147.2\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"151.2\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >6<\/text><line x1=\"62\" y1=\"95.6\" x2=\"464\" y2=\"95.6\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"99.6\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >8<\/text><line x1=\"62\" y1=\"44.0\" x2=\"464\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >10<\/text><line x1=\"62\" y1=\"302\" x2=\"464\" y2=\"302\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"173.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 173.0)\">No. of participants<\/text><rect x=\"92.2\" y=\"147.2\" width=\"68.3\" height=\"154.8\" rx=\"3\" fill=\"#0089CC\"\/><text x=\"126.3\" y=\"140.2\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">6<\/text><rect x=\"164.5\" y=\"224.6\" width=\"68.3\" height=\"77.4\" rx=\"3\" fill=\"#B8C4CC\"\/><text x=\"198.7\" y=\"217.6\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">3<\/text><text x=\"162.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T2<\/text><text x=\"162.5\" y=\"335.0\" font-size=\"11.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >3 months<\/text><rect x=\"293.2\" y=\"121.4\" width=\"68.3\" height=\"180.6\" rx=\"3\" fill=\"#0089CC\"\/><text x=\"327.3\" y=\"114.4\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">7<\/text><rect x=\"365.5\" y=\"173.0\" width=\"68.3\" height=\"129.0\" rx=\"3\" fill=\"#B8C4CC\"\/><text x=\"399.7\" y=\"166.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">5<\/text><text x=\"363.5\" y=\"320.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >T3<\/text><text x=\"363.5\" y=\"335.0\" font-size=\"11.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >6 months<\/text><\/svg><\/div><\/div><div class=\"dx-legend\"><span><i style=\"background:#0089CC\"><\/i>Group A<\/span><span><i style=\"background:#B8C4CC\"><\/i>Group B<\/span><\/div><div class=\"dx-fig-note\">*p&lt;0.05<\/div><\/figure>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>TENDOFORTE\u00ae \u2014 athletes with chronic ankle instability<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">50 athletes \u00b7 Double-blind, randomized, placebo-controlled clinical study \u00b7 5 g\/day for 6 months<\/div>\n          <p>Assessment using the CAIT (perceived instability and pain, 0\u201330) and FAAM-G (functional assessment of ankle and foot, 0\u2013100) scales.<\/p>\n          <div class=\"table-scroll\" style=\"margin:18px 0;\">\n            <table class=\"path-table\" style=\"font-size:13.5px;\">\n              <thead><tr><th>Scale<\/th><th>Group<\/th><th>Baseline (T0)<\/th><th>6 months (T1)<\/th><th>p-value<\/th><\/tr><\/thead>\n              <tbody>\n                <tr><td>CAIT<\/td><td>Tendoforte\u00ae<\/td><td>15.48<\/td><td>20.76<\/td><td>&lt;0.05<\/td><\/tr>\n                <tr><td>CAIT<\/td><td>Placebo<\/td><td>20.80<\/td><td>21.45<\/td><td>\u2014<\/td><\/tr>\n                <tr><td>FAAM-G ADL (%)<\/td><td>Tendoforte\u00ae<\/td><td>81.56<\/td><td>91.32<\/td><td>&lt;0.05<\/td><\/tr>\n                <tr><td>FAAM-G ADL (%)<\/td><td>Placebo<\/td><td>90.28<\/td><td>91.44<\/td><td>\u2014<\/td><\/tr>\n                <tr><td>FAAM-G Sport (%)<\/td><td>Tendoforte\u00ae<\/td><td>60.48<\/td><td>80.36<\/td><td>&lt;0.05<\/td><\/tr>\n                <tr><td>FAAM-G Sport (%)<\/td><td>Placebo<\/td><td>76.24<\/td><td>76.52<\/td><td>\u2014<\/td><\/tr>\n              <\/tbody>\n            <\/table>\n          <\/div>\n          <p style=\"margin-bottom:6px;\">3-month follow-up \u2014 reduction in ankle sprains: <b>24\/25<\/b> in the Tendoforte\u00ae group versus <b>9\/25<\/b> in the placebo group (p&lt;0.001).<\/p>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>Astaxanthin \u2014 anti-inflammatory action and effect on collagen<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">Eur J Nutr, 2010 \u00b7 Preclinical model in adult rabbits<\/div>\n          <p>Astaxanthin suppresses the expression of scavenger receptors and the activity of matrix metalloproteinases (MMP) in macrophages, reducing TNF-\u03b1, IL-1\u03b2, IL-6 and COX-2.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Astaxanthin in macrophages \u00b7 expression relative to \u03b2-actin<\/div><div class=\"dx-fig-grid cols-2 keep-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"TNF-\u03b1\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >TNF-\u03b1<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.0<\/text><line x1=\"62\" y1=\"185.3\" x2=\"364\" y2=\"185.3\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"189.3\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.5<\/text><line x1=\"62\" y1=\"114.7\" x2=\"364\" y2=\"114.7\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"118.7\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.0<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.5<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">TNF-\u03b1\/\u03b2-actin<\/text><rect x=\"76.3\" y=\"158.5\" width=\"46.8\" height=\"97.5\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M99.8 151.4V158.5M92.8 151.4H106.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"120.3\" width=\"46.8\" height=\"135.7\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 104.8V120.3M168.2 104.8H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"209.4\" width=\"46.8\" height=\"46.6\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 205.1V209.4M243.8 205.1H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"199.1\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">**<\/text><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"203.7\" width=\"46.8\" height=\"52.3\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 192.4V203.7M319.2 192.4H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"186.4\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">**<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"IL-1\u03b2\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >IL-1\u03b2<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.0<\/text><line x1=\"62\" y1=\"203.0\" x2=\"364\" y2=\"203.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"207.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.5<\/text><line x1=\"62\" y1=\"150.0\" x2=\"364\" y2=\"150.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"154.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.0<\/text><line x1=\"62\" y1=\"97.0\" x2=\"364\" y2=\"97.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"101.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1.5<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2.0<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">IL-1\u03b2\/\u03b2-actin<\/text><rect x=\"76.3\" y=\"250.7\" width=\"46.8\" height=\"5.3\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M99.8 249.6V250.7M92.8 249.6H106.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"65.2\" width=\"46.8\" height=\"190.8\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 62.0V65.2M168.2 62.0H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"157.4\" width=\"46.8\" height=\"98.6\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 155.3V157.4M243.8 155.3H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"149.3\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"196.6\" width=\"46.8\" height=\"59.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 194.5V196.6M319.2 194.5H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"188.5\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"IL-6\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >IL-6<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"185.3\" x2=\"364\" y2=\"185.3\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"189.3\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2<\/text><line x1=\"62\" y1=\"114.7\" x2=\"364\" y2=\"114.7\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"118.7\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >6<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">IL-6\/\u03b2-actin (\u00d710\u207b\u2075)<\/text><rect x=\"76.3\" y=\"215.4\" width=\"46.8\" height=\"40.6\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M99.8 197.7V215.4M92.8 197.7H106.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"79.3\" width=\"46.8\" height=\"176.7\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 68.7V79.3M168.2 68.7H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"171.2\" width=\"46.8\" height=\"84.8\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 167.0V171.2M243.8 167.0H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"161.0\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"204.8\" width=\"46.8\" height=\"51.2\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 197.7V204.8M319.2 197.7H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"191.7\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"COX-2\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >COX-2<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.00<\/text><line x1=\"62\" y1=\"203.0\" x2=\"364\" y2=\"203.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"207.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.05<\/text><line x1=\"62\" y1=\"150.0\" x2=\"364\" y2=\"150.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"154.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.10<\/text><line x1=\"62\" y1=\"97.0\" x2=\"364\" y2=\"97.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"101.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.15<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.20<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">COX-2\/\u03b2-actin<\/text><rect x=\"76.3\" y=\"176.5\" width=\"46.8\" height=\"79.5\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M99.8 174.4V176.5M92.8 174.4H106.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"97.0\" width=\"46.8\" height=\"159.0\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 90.6V97.0M168.2 90.6H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"200.9\" width=\"46.8\" height=\"55.1\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 198.8V200.9M243.8 198.8H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"192.8\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"227.4\" width=\"46.8\" height=\"28.6\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 225.3V227.4M319.2 225.3H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"219.3\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"MMP-2\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >MMP-2<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.0<\/text><line x1=\"62\" y1=\"203.0\" x2=\"364\" y2=\"203.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"207.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.2<\/text><line x1=\"62\" y1=\"150.0\" x2=\"364\" y2=\"150.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"154.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.4<\/text><line x1=\"62\" y1=\"97.0\" x2=\"364\" y2=\"97.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"101.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.6<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0.8<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">MMP-2\/\u03b2-actin<\/text><rect x=\"76.3\" y=\"181.8\" width=\"46.8\" height=\"74.2\" rx=\"3\" fill=\"#B8C4CC\"\/><path d=\"M99.8 176.5V181.8M92.8 176.5H106.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"86.4\" width=\"46.8\" height=\"169.6\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 75.8V86.4M168.2 75.8H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"118.2\" width=\"46.8\" height=\"137.8\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 102.3V118.2M243.8 102.3H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"142.1\" width=\"46.8\" height=\"113.9\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 131.5V142.1M319.2 131.5H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"125.5\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 380 330\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"MMP-9\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"190.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >MMP-9<\/text><line x1=\"62\" y1=\"256.0\" x2=\"364\" y2=\"256.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"62\" y1=\"213.6\" x2=\"364\" y2=\"213.6\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"217.6\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >5<\/text><line x1=\"62\" y1=\"171.2\" x2=\"364\" y2=\"171.2\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"175.2\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >10<\/text><line x1=\"62\" y1=\"128.8\" x2=\"364\" y2=\"128.8\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"132.8\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >15<\/text><line x1=\"62\" y1=\"86.4\" x2=\"364\" y2=\"86.4\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"90.4\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >20<\/text><line x1=\"62\" y1=\"44.0\" x2=\"364\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >25<\/text><line x1=\"62\" y1=\"256\" x2=\"364\" y2=\"256\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 150.0)\">MMP-9\/\u03b2-actin<\/text><rect x=\"76.3\" y=\"256.0\" width=\"46.8\" height=\"0.0\" rx=\"3\" fill=\"#B8C4CC\"\/><text x=\"99.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"151.8\" y=\"79.6\" width=\"46.8\" height=\"176.4\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M175.2 76.2V79.6M168.2 76.2H182.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"175.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >0<\/text><rect x=\"227.3\" y=\"162.7\" width=\"46.8\" height=\"93.3\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M250.8 158.5V162.7M243.8 158.5H257.8\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"250.8\" y=\"152.5\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"250.8\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >5<\/text><rect x=\"302.8\" y=\"205.1\" width=\"46.8\" height=\"50.9\" rx=\"3\" fill=\"#0089CC\"\/><path d=\"M326.2 203.4V205.1M319.2 203.4H333.2\" stroke=\"#052A3D\" stroke-width=\"1.4\" fill=\"none\"\/><text x=\"326.2\" y=\"197.4\" font-size=\"13\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">***<\/text><text x=\"326.2\" y=\"274.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >10<\/text><line x1=\"68.0\" y1=\"290\" x2=\"131.5\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"99.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >monocytes<\/text><line x1=\"143.5\" y1=\"290\" x2=\"358.0\" y2=\"290\" stroke=\"#29ABE8\" stroke-width=\"1.4\"\/><text x=\"250.8\" y=\"306.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >macrophages<\/text><\/svg><\/div><\/div><div class=\"dx-fig-note\">astaxanthin (\u00b5M) \u2014 *p&lt;0.05 \u00b7 **p&lt;0.01 \u00b7 ***p&lt;0.001 \u00b7 ****p&lt;0.0001<\/div><\/figure>\n          <p style=\"margin-top:18px;\">In a preclinical model with 32 adult rabbits (4 mg\/day for 3 weeks), astaxanthin increases tendon tensile strength and decreases type III collagen production in favor of type I collagen.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Astaxanthin \u00b7 preclinical model in adult rabbits<\/div><div class=\"dx-fig-grid cols-2\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"Tendon tensile strength\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Tendon tensile strength<\/text><line x1=\"62\" y1=\"310.0\" x2=\"464\" y2=\"310.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >88<\/text><line x1=\"62\" y1=\"264.1\" x2=\"464\" y2=\"264.1\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"268.1\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >89<\/text><line x1=\"62\" y1=\"218.3\" x2=\"464\" y2=\"218.3\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"222.3\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >90<\/text><line x1=\"62\" y1=\"172.4\" x2=\"464\" y2=\"172.4\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"176.4\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >91<\/text><line x1=\"62\" y1=\"126.6\" x2=\"464\" y2=\"126.6\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"130.6\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >92<\/text><line x1=\"62\" y1=\"80.7\" x2=\"464\" y2=\"80.7\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"84.7\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >93<\/text><line x1=\"62\" y1=\"310\" x2=\"464\" y2=\"310\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"177.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 177.0)\">Tensile strength<\/text><path d=\"M162.5 99.0L363.5 287.1\" stroke=\"#B8C4CC\" stroke-width=\"2.2\" stroke-dasharray=\"6 5\"\/><circle cx=\"162.5\" cy=\"99.0\" r=\"9\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"2\"\/><text x=\"162.5\" y=\"81.0\" font-size=\"13\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">92.6<\/text><text x=\"162.5\" y=\"330.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Astaxanthin (+)<\/text><circle cx=\"363.5\" cy=\"287.1\" r=\"9\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"2\"\/><text x=\"363.5\" y=\"269.1\" font-size=\"13\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">88.5<\/text><text x=\"363.5\" y=\"330.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Astaxanthin (\u2212)<\/text><\/svg><\/div><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 480 360\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"Type III\/I collagen ratio\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><text x=\"240.0\" y=\"24.0\" font-size=\"15.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Type III\/I collagen ratio<\/text><line x1=\"62\" y1=\"310.0\" x2=\"464\" y2=\"310.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"314.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1000<\/text><line x1=\"62\" y1=\"256.8\" x2=\"464\" y2=\"256.8\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"260.8\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2000<\/text><line x1=\"62\" y1=\"203.6\" x2=\"464\" y2=\"203.6\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"207.6\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >3000<\/text><line x1=\"62\" y1=\"150.4\" x2=\"464\" y2=\"150.4\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"154.4\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4000<\/text><line x1=\"62\" y1=\"97.2\" x2=\"464\" y2=\"97.2\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"101.2\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >5000<\/text><line x1=\"62\" y1=\"44.0\" x2=\"464\" y2=\"44.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"54.0\" y=\"48.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >6000<\/text><line x1=\"62\" y1=\"310\" x2=\"464\" y2=\"310\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"177.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 177.0)\">Collagen III\/I<\/text><path d=\"M162.5 251.5V269.0M162.5 282.3V292.4M144.4 251.5H180.6M144.4 292.4H180.6\" stroke=\"#54697A\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"126.3\" y=\"269.0\" width=\"72.4\" height=\"13.3\" rx=\"3\" fill=\"#0089CC\" opacity=\".85\"\/><line x1=\"126.3\" y1=\"273.3\" x2=\"198.7\" y2=\"273.3\" stroke=\"#052A3D\" stroke-width=\"2.4\"\/><circle cx=\"162.5\" cy=\"238.2\" r=\"4\" fill=\"#fff\" stroke=\"#54697A\" stroke-width=\"1.4\"\/><text x=\"162.5\" y=\"330.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Astaxanthin (+)<\/text><path d=\"M363.5 60.0V103.6M363.5 192.4V213.2M345.4 60.0H381.6M345.4 213.2H381.6\" stroke=\"#54697A\" stroke-width=\"1.4\" fill=\"none\"\/><rect x=\"327.3\" y=\"103.6\" width=\"72.4\" height=\"88.8\" rx=\"3\" fill=\"#B8C4CC\" opacity=\".85\"\/><line x1=\"327.3\" y1=\"154.7\" x2=\"399.7\" y2=\"154.7\" stroke=\"#052A3D\" stroke-width=\"2.4\"\/><text x=\"363.5\" y=\"330.0\" font-size=\"12.5\" fill=\"#052A3D\" text-anchor=\"middle\" font-weight=\"700\" >Astaxanthin (\u2212)<\/text><\/svg><\/div><\/div><\/figure>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>Veri\u00b7Sperse\u00ae trans-resveratrol \u2014 bioavailability<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">Comparative bioavailability study \u00b7 Patented LipiSperse\u00ae technology<\/div>\n          <p>Thanks to its patented dispersion technology, Veri\u00b7Sperse\u00ae trans-resveratrol achieves a water suspension capacity about 6,000 times higher than standard trans-resveratrol. Its bioavailability is three times higher than that of standard trans-resveratrol administered at the same concentration.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Plasma concentration of trans-resveratrol<\/div><div class=\"dx-fig-grid cols-1\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 760 400\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><line x1=\"74\" y1=\"346.0\" x2=\"736\" y2=\"346.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"350.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"74\" y1=\"271.0\" x2=\"736\" y2=\"271.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"275.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >1000<\/text><line x1=\"74\" y1=\"196.0\" x2=\"736\" y2=\"196.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"200.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >2000<\/text><line x1=\"74\" y1=\"121.0\" x2=\"736\" y2=\"121.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"125.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >3000<\/text><line x1=\"74\" y1=\"46.0\" x2=\"736\" y2=\"46.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"50.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >4000<\/text><line x1=\"74\" y1=\"346\" x2=\"736\" y2=\"346\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"196.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 196.0)\">Plasma concentration (ng\/ml)<\/text><line x1=\"74.0\" y1=\"346\" x2=\"74.0\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"74.0\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >0<\/text><line x1=\"184.3\" y1=\"346\" x2=\"184.3\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"184.3\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >2<\/text><line x1=\"294.7\" y1=\"346\" x2=\"294.7\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"294.7\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >4<\/text><line x1=\"405.0\" y1=\"346\" x2=\"405.0\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"405.0\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >6<\/text><line x1=\"515.3\" y1=\"346\" x2=\"515.3\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"515.3\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >8<\/text><line x1=\"625.7\" y1=\"346\" x2=\"625.7\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"625.7\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >10<\/text><line x1=\"736.0\" y1=\"346\" x2=\"736.0\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"736.0\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >12<\/text><text x=\"736.0\" y=\"388.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"end\" font-weight=\"700\" >Time (h)<\/text><path d=\"M74.0 346.0 L101.6 261.2 L129.2 304.0 L184.3 327.2 L239.5 334.8 L294.7 330.2 L349.8 328.8 L405.0 331.0 L515.3 337.0 L736.0 340.0\" stroke=\"#B8C4CC\" stroke-width=\"2.4\" fill=\"none\" stroke-linejoin=\"round\"\/><circle cx=\"74.0\" cy=\"346.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"101.6\" cy=\"261.2\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"129.2\" cy=\"304.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"184.3\" cy=\"327.2\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"239.5\" cy=\"334.8\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"294.7\" cy=\"330.2\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"349.8\" cy=\"328.8\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"405.0\" cy=\"331.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"515.3\" cy=\"337.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"736.0\" cy=\"340.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><path d=\"M74.0 346.0 L101.6 304.0 L129.2 239.5 L184.3 301.0 L239.5 316.8 L294.7 320.5 L349.8 326.5 L405.0 324.2 L515.3 334.8 L736.0 338.5\" stroke=\"#7CC7EA\" stroke-width=\"2.4\" fill=\"none\" stroke-linejoin=\"round\"\/><circle cx=\"74.0\" cy=\"346.0\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"101.6\" cy=\"304.0\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"129.2\" cy=\"239.5\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"184.3\" cy=\"301.0\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"239.5\" cy=\"316.8\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"294.7\" cy=\"320.5\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"349.8\" cy=\"326.5\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"405.0\" cy=\"324.2\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"515.3\" cy=\"334.8\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"736.0\" cy=\"338.5\" r=\"5\" fill=\"#7CC7EA\" stroke=\"#fff\" stroke-width=\"1.5\"\/><path d=\"M74.0 346.0 L101.6 116.5 L129.2 190.0 L184.3 290.5 L239.5 320.5 L294.7 322.0 L349.8 328.0 L405.0 331.0 L515.3 341.5 L736.0 342.2\" stroke=\"#0089CC\" stroke-width=\"2.4\" fill=\"none\" stroke-linejoin=\"round\"\/><circle cx=\"74.0\" cy=\"346.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"101.6\" cy=\"116.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"129.2\" cy=\"190.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"184.3\" cy=\"290.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"239.5\" cy=\"320.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"294.7\" cy=\"322.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"349.8\" cy=\"328.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"405.0\" cy=\"331.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"515.3\" cy=\"341.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"736.0\" cy=\"342.2\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><\/svg><\/div><\/div><div class=\"dx-legend\"><span><i style=\"background:#0089CC\"><\/i>150 mg Veri\u00b7Sperse\u00ae<\/span><span><i style=\"background:#7CC7EA\"><\/i>75 mg Veri\u00b7Sperse\u00ae<\/span><span><i style=\"background:#B8C4CC\"><\/i>150 mg standard trans-resveratrol<\/span><\/div><\/figure>\n        <\/div>\n      <\/details>\n\n      <details class=\"ev-item\">\n        <summary>Bioactive collagen peptides \u2014 presence in tissue<span class=\"ev-plus\">+<\/span><\/summary>\n        <div class=\"ev-body\">\n          <div class=\"ev-meta\">Ex vivo preclinical model<\/div>\n          <p>14C-labeled bioactive collagen peptides show high absorption and a greater affinity for connective tissue than free proline, with sustained presence up to 192 hours \u2014 supporting the synthesis of new type I collagen, essential for tendon function.<\/p>\n          <figure class=\"dx-fig\"><div class=\"dx-fig-title\">Bioactive collagen peptides \u00b7 presence in connective tissue (ex vivo model)<\/div><div class=\"dx-fig-grid cols-1\"><div class=\"dx-fig-panel\"><svg viewBox=\"0 0 760 400\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\" role=\"img\" aria-label=\"\" font-family=\"Inter,-apple-system,BlinkMacSystemFont,sans-serif\"><line x1=\"74\" y1=\"346.0\" x2=\"736\" y2=\"346.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"350.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >0<\/text><line x1=\"74\" y1=\"246.0\" x2=\"736\" y2=\"246.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"250.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >20<\/text><line x1=\"74\" y1=\"146.0\" x2=\"736\" y2=\"146.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"150.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >40<\/text><line x1=\"74\" y1=\"46.0\" x2=\"736\" y2=\"46.0\" stroke=\"#E2ECF2\" stroke-width=\"1\"\/><text x=\"66.0\" y=\"50.0\" font-size=\"12.5\" fill=\"#7C8D9B\" text-anchor=\"end\" font-weight=\"500\" >60<\/text><line x1=\"74\" y1=\"346\" x2=\"736\" y2=\"346\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"16.0\" y=\"196.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" transform=\"rotate(-90 16 196.0)\">Bq\/g of tissue<\/text><line x1=\"74.0\" y1=\"346\" x2=\"74.0\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"74.0\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >0<\/text><line x1=\"202.1\" y1=\"346\" x2=\"202.1\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"202.1\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >24<\/text><line x1=\"330.3\" y1=\"346\" x2=\"330.3\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"330.3\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >48<\/text><line x1=\"458.4\" y1=\"346\" x2=\"458.4\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"458.4\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >72<\/text><line x1=\"586.5\" y1=\"346\" x2=\"586.5\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"586.5\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >96<\/text><line x1=\"736.0\" y1=\"346\" x2=\"736.0\" y2=\"351\" stroke=\"#7C8D9B\"\/><text x=\"736.0\" y=\"366.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"middle\" font-weight=\"600\" >192<\/text><path d=\"M730.0 352l6 -12M736.0 352l6 -12\" stroke=\"#7C8D9B\" stroke-width=\"1.2\"\/><text x=\"736.0\" y=\"388.0\" font-size=\"12.5\" fill=\"#54697A\" text-anchor=\"end\" font-weight=\"700\" >Time (h)<\/text><path d=\"M106.0 253.5 L127.4 266.0 L159.4 258.5 L212.8 253.5 L330.3 268.5 L586.5 271.0\" stroke=\"#B8C4CC\" stroke-width=\"2.4\" fill=\"none\" stroke-linejoin=\"round\"\/><circle cx=\"106.0\" cy=\"253.5\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"127.4\" cy=\"266.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"159.4\" cy=\"258.5\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"212.8\" cy=\"253.5\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"330.3\" cy=\"268.5\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"586.5\" cy=\"271.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"736.0\" cy=\"291.0\" r=\"5\" fill=\"#B8C4CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><path d=\"M106.0 256.0 L127.4 223.5 L159.4 163.5 L212.8 178.5 L330.3 148.5 L586.5 158.5\" stroke=\"#0089CC\" stroke-width=\"2.4\" fill=\"none\" stroke-linejoin=\"round\"\/><circle cx=\"106.0\" cy=\"256.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"127.4\" cy=\"223.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"159.4\" cy=\"163.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"212.8\" cy=\"178.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"330.3\" cy=\"148.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"586.5\" cy=\"158.5\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><circle cx=\"736.0\" cy=\"286.0\" r=\"5\" fill=\"#0089CC\" stroke=\"#fff\" stroke-width=\"1.5\"\/><text x=\"159.4\" y=\"151.5\" font-size=\"18\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><text x=\"212.8\" y=\"166.5\" font-size=\"18\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><text x=\"330.3\" y=\"136.5\" font-size=\"18\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><text x=\"586.5\" y=\"146.5\" font-size=\"18\" fill=\"#0089CC\" text-anchor=\"middle\" font-weight=\"800\" stroke=\"#fff\" stroke-width=\"4\" paint-order=\"stroke\" stroke-linejoin=\"round\">*<\/text><\/svg><\/div><\/div><div class=\"dx-legend\"><span><i style=\"background:#0089CC\"><\/i>[\u00b9\u2074C] bioactive collagen peptides<\/span><span><i style=\"background:#B8C4CC\"><\/i>[\u00b9\u2074C] free proline<\/span><\/div><\/figure>\n        <\/div>\n      <\/details>\n\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ MODE OF USE ============ -->\n<section class=\"section-pad\" id=\"modo-empleo\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">How to use<\/div>\n      <h2>A clear protocol, <em>in two phases<\/em><\/h2>\n    <\/div>\n\n    <div class=\"dose-band reveal\">\n      <div class=\"dose-band-photo\">\n        <img decoding=\"async\" src=\"https:\/\/order-science.com\/wp-content\/uploads\/2026\/08\/foto-doltendix-1.png\" alt=\"Preparing a Doltendix sachet in water\">\n      <\/div>\n      <div class=\"dose-band-content\">\n        <div class=\"dose-phase\">\n          <div class=\"phase-block\"><b>2 sachets<\/b><span>a day, for 10 days<\/span><\/div>\n          <div class=\"phase-block\"><b>1 sachet<\/b><span>a day, for 20 days<\/span><\/div>\n        <\/div>\n        <p style=\"color:#DCF1FC;margin:0;\">A dietary supplement designed to support the daily nutrition of tendons and ligaments, at any stage of your routine.<\/p>\n      <\/div>\n    <\/div>\n\n    <div class=\"timeline reveal\">\n      <div class=\"tl-step\"><span>Everyday activity<\/span><\/div>\n      <div class=\"tl-step\"><span>Training routine<\/span><\/div>\n      <div class=\"tl-step\"><span>Daily nutrition<\/span><\/div>\n      <div class=\"tl-step\"><span>Ongoing supplementation<\/span><\/div>\n    <\/div>\n\n    <div class=\"section-head reveal mt-40\" style=\"margin-top:64px;\">\n      <h3>One formula, four components<\/h3>\n    <\/div>\n    <div class=\"indications-grid reveal\">\n      <div class=\"ind-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M4 4c4 0 4 4 8 4s4-4 8-4M4 12c4 0 4 4 8 4s4-4 8-4M4 20c4 0 4 4 8 4s4-4 8-4\"><\/path><\/svg>\n        <span>TENDOFORTE\u00ae \u2014 5,000 mg of bioactive collagen peptides<\/span>\n      <\/div>\n      <div class=\"ind-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><circle cx=\"12\" cy=\"12\" r=\"4\"><\/circle><path d=\"M12 2v3M12 19v3M2 12h3M19 12h3M4.9 4.9l2.1 2.1M17 17l2.1 2.1M4.9 19.1L7 17M17 7l2.1-2.1\"><\/path><\/svg>\n        <span>AstaReal\u00ae \u2014 8 mg of astaxanthin<\/span>\n      <\/div>\n      <div class=\"ind-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 2v20M4 8l8-6 8 6M6 20h12\"><\/path><\/svg>\n        <span>Veri\u00b7Sperse\u00ae \u2014 150 mg of trans-resveratrol<\/span>\n      <\/div>\n      <div class=\"ind-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 3l1.9 5.8H20l-4.9 3.6 1.9 5.8L12 14.6l-4.9 3.6 1.9-5.8L4 8.8h6.1z\"><\/path><\/svg>\n        <span>Vitamin C \u2014 500 mg (625% NRV)<\/span>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ SPRAIN FLOW ============ -->\n<section class=\"section-pad\" style=\"background:var(--paper);\">\n  <div class=\"container\">\n    <div class=\"section-head center reveal\" style=\"margin-left:auto;margin-right:auto;\">\n      <div class=\"eyebrow\">The science behind Doltendix\u00ae<\/div>\n      <h2>From the formula to <em>published research<\/em><\/h2>\n      <p>Four selected ingredients, combined in a single formula and backed by published experimental and clinical studies.<\/p>\n    <\/div>\n    <div class=\"flow-wrap reveal\">\n      <div class=\"flow-row\">\n        <div class=\"flow-col a\">\n          <div class=\"head\">Formulation<\/div>\n          <ul><li>Bioactive collagen peptides<\/li><li>Astaxanthin<\/li><li>Trans-resveratrol<\/li><li>Vitamin C<\/li><\/ul>\n          <div class=\"check\">4 selected ingredients<\/div>\n        <\/div>\n        <div class=\"flow-col b\">\n          <div class=\"head\">Scientific research<\/div>\n          <ul><li>In vitro studies<\/li><li>Preclinical models<\/li><li>Clinical studies<\/li><\/ul>\n          <div class=\"check\">Published results<\/div>\n        <\/div>\n        <div class=\"flow-col c\">\n          <div class=\"head\">Daily supplementation<\/div>\n          <ul><li>2 sachets\/day \u00d7 10 days<\/li><li>1 sachet\/day \u00d7 20 days<\/li><\/ul>\n          <div class=\"nocheck\">Recommended use<\/div>\n        <\/div>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n\n<!-- ============ QUALITY \/ CERTS ============ -->\n<section class=\"section-pad\" style=\"background:var(--paper);\">\n  <div class=\"container\">\n    <div class=\"section-head reveal\">\n      <div class=\"eyebrow\">Quality and commitment<\/div>\n      <h2>Kolinpharma\u00ae guarantees <em>high quality standards<\/em><\/h2>\n      <p>Kolinpharma\u00ae applies high quality standards, from formulation to the marketing of its nutraceutical solutions.<\/p>\n    <\/div>\n    <div class=\"cert-grid reveal\">\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 2l7 4v6c0 5-3.5 8-7 10-3.5-2-7-5-7-10V6z\"><\/path><\/svg>\n        <h4>ISO 22000<\/h4>\n        <p>Guarantee of food hygiene and safety in the agri-food sector.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M3 12h18M12 3v18M5 5l14 14M19 5L5 19\"><\/path><\/svg>\n        <h4>ISO 14001<\/h4>\n        <p>Monitoring of activities with a significant environmental impact.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M9 12l2 2 4-4\"><\/path><circle cx=\"12\" cy=\"12\" r=\"9\"><\/circle><\/svg>\n        <h4>ISO 9001<\/h4>\n        <p>Standards for quality management systems.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 2v20M2 12h20\"><\/path><circle cx=\"12\" cy=\"12\" r=\"9\"><\/circle><\/svg>\n        <h4>Jewish and Muslim doctrines<\/h4>\n        <p>High quality standards in line with both religious doctrines.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 2l2.4 6.6L21 11l-6.6 2.4L12 20l-2.4-6.6L3 11l6.6-2.4z\"><\/path><\/svg>\n        <h4>Not on the WADA list<\/h4>\n        <p>Free of substances on the World Anti-Doping Agency list.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><rect x=\"3\" y=\"7\" width=\"18\" height=\"13\" rx=\"2\"><\/rect><path d=\"M8 7V5a4 4 0 018 0v2\"><\/path><\/svg>\n        <h4>Anti-counterfeiting system<\/h4>\n        <p>Tamper-evident opening to guarantee product integrity.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M2 12s4-7 10-7 10 7 10 7-4 7-10 7-10-7-10-7z\"><\/path><circle cx=\"12\" cy=\"12\" r=\"3\"><\/circle><\/svg>\n        <h4>Low vision<\/h4>\n        <p>Packaging designed with people with low vision in mind.<\/p>\n      <\/div>\n      <div class=\"cert-card\">\n        <svg class=\"ic\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"currentColor\" stroke-width=\"1.6\"><path d=\"M12 2v20M4 6h16M4 18h16\"><\/path><\/svg>\n        <h4>Gluten- and lactose-free<\/h4>\n        <p>Formulated to ensure safety and closeness to the consumer.<\/p>\n      <\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ PATENT ============ -->\n<section class=\"section-pad\">\n  <div class=\"container\">\n    <div class=\"patent-sec reveal\">\n      <div class=\"eyebrow\" style=\"color:var(--blue-500);justify-content:center;\">Patent<\/div>\n      <h2>A unique and <em>innovative<\/em> product<\/h2>\n      <div class=\"patent-flags\">\n        <span class=\"flag-chip\">\ud83c\uddee\ud83c\uddf9 Patented in Italy<\/span>\n        <span class=\"flag-chip\">\ud83c\udde8\ud83c\uddf3 Patented in China<\/span>\n      <\/div>\n      <p style=\"font-size:12.5px;color:#B9D6E4;max-width:520px;margin:0 auto 10px;\">Title registered in the patent application:<\/p>\n      <p class=\"patent-quote\" style=\"font-size:clamp(15px,2vw,20px);\">\u201cComposition useful for the treatment of tendinopathies\u201d<\/p>\n      <p style=\"font-size:11.5px;color:#B9D6E4;max-width:520px;margin:14px auto 0;\">Technical title registered in the patent application; it does not constitute an authorized therapeutic indication for marketing the product as a dietary supplement.<\/p>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ FAQ ============ -->\n<section class=\"section-pad\" style=\"background:var(--paper);\" id=\"faq\">\n  <div class=\"container\">\n    <div class=\"section-head center reveal\" style=\"margin-left:auto;margin-right:auto;\">\n      <div class=\"eyebrow\">Frequently asked questions<\/div>\n      <h2>Everything you need <em>to know<\/em><\/h2>\n    <\/div>\n    <div class=\"faq-list reveal\">\n      <details class=\"faq\" open=\"\">\n        <summary>What is Doltendix\u00ae?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>It is a dietary supplement formulated by Kolinpharma\u00ae that combines tendon-specific bioactive collagen peptides (TENDOFORTE\u00ae), astaxanthin (AstaReal\u00ae), trans-resveratrol (Veri\u00b7Sperse\u00ae) and vitamin C, designed to complement the nutrition of tendons and ligaments.<\/p>\n      <\/details>\n      <details class=\"faq\">\n        <summary>How do I take it?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>The usual protocol is 2 sachets a day for 10 days, followed by 1 sachet a day for 20 days. Each sachet contains 5 g, with sweetener.<\/p>\n      <\/details>\n      <details class=\"faq\">\n        <summary>What sets Doltendix\u00ae apart from other collagen supplements?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>It provides 5000 mg of specific collagen (bioactive peptides) per daily dose \u2014 the highest concentration available on the market according to the comparison published by Kolinpharma\u00ae \u2014 combined with astaxanthin, trans-resveratrol and vitamin C in a patented formula.<\/p>\n      <\/details>\n      <details class=\"faq\">\n        <summary>Is it backed by clinical studies?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>Yes. The full formula has an in vitro study on human tenocytes and a real-life study in 150 patients with epicondylitis. In addition, its active ingredients (TENDOFORTE\u00ae, astaxanthin, trans-resveratrol and vitamin C) have their own studies, including two double-blind clinical trials with athletes.<\/p>\n      <\/details>\n      <details class=\"faq\">\n        <summary>Is it patented?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>Yes, Doltendix\u00ae is patented in Italy and China. The patent application registers the composition under the technical title \u201cuseful for the treatment of tendinopathies\u201d, a registration title that is not equivalent to an authorized therapeutic indication for marketing it as a dietary supplement.<\/p>\n      <\/details>\n      <details class=\"faq\">\n        <summary>What quality controls does it have?<span class=\"ev-plus\">+<\/span><\/summary>\n        <p>Kolinpharma\u00ae certifies its processes under ISO 9001, ISO 14001 and ISO 22000, and the product meets standards in line with Jewish and Muslim doctrines, contains no substances on the WADA list, has a tamper-evident opening system, is designed with people with low vision in mind, and is gluten- and lactose-free.<\/p>\n      <\/details>\n    <\/div>\n  <\/div>\n<\/section>\n\n<!-- ============ FINAL CTA ============ -->\n<section class=\"section-pad\" id=\"contacto\">\n  <div class=\"container\">\n    <div class=\"final-cta reveal\">\n      <h2><em style=\"color:#fff;\">Daily supplementation<\/em> for tendons and ligaments<\/h2>\n      <p>Tendon-specific collagen at its highest dose, astaxanthin, trans-resveratrol and vitamin C \u2014 a dietary supplement backed by scientific evidence and patented in Italy and China.<\/p>\n      <div class=\"buy-row center\">\n        <div class=\"qty-selector qty-selector-cta\" role=\"group\" aria-label=\"Quantity\">\n          <button type=\"button\" class=\"qty-btn qty-minus\" aria-label=\"Decrease quantity\">\u2212<\/button>\n          <input type=\"number\" class=\"qty-input\" value=\"1\" min=\"1\" max=\"99\" inputmode=\"numeric\" aria-label=\"Quantity\">\n          <button type=\"button\" class=\"qty-btn qty-plus\" aria-label=\"Increase quantity\">+<\/button>\n        <\/div>\n        <a href=\"https:\/\/order-science.com\/checkout\/?add-to-cart=400&amp;quantity=1\" class=\"btn btn-white btn-buy doltendix-buy-link\" data-base-url=\"https:\/\/order-science.com\/checkout\/?add-to-cart=400\" data-product-id=\"400\" target=\"_blank\" rel=\"noopener\">\n          <span class=\"cta-label\">Add to cart<\/span>\n          <span class=\"cta-price\">$75.000<\/span>\n        <\/a>\n      <\/div>\n      <div style=\"margin-top:20px;font-size:12.5px;color:#DCF1FC;\">Patented in Italy and China \u00b7 Kolinpharma\u00ae \u00b7 Manufactured under ISO 9001 \u00b7 14001 \u00b7 22000<\/div>\n    <\/div>\n  <\/div>\n<\/section>\n\n<script>\ndocument.documentElement.classList.add('js-ready');\n\n\/\/ staggered reveal on scroll\nconst revealEls = document.querySelectorAll('.reveal');\nconst io = new IntersectionObserver((entries)=>{\n  entries.forEach((e)=>{\n    if(e.isIntersecting){\n      const el = e.target;\n      const group = el.parentElement ? el.parentElement.querySelectorAll('.reveal') : [el];\n      let delay = 0;\n      group.forEach((g,i)=>{ if(g===el) delay = i*70; });\n      setTimeout(()=>el.classList.add('in'), Math.min(delay,280));\n      io.unobserve(el);\n    }\n  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clamp(parseInt(input.value,10) + 1);\n    updateLink();\n  });\n  input.addEventListener('input', () => {\n    input.value = input.value.replace(\/[^0-9]\/g,'');\n  });\n  input.addEventListener('change', () => {\n    input.value = clamp(input.value);\n    updateLink();\n  });\n});\n\n\/\/ Agregar al carrito v\u00eda AJAX de WooCommerce (sin salir de la p\u00e1gina),\n\/\/ para que el carrito lateral del sitio se abra en vez de ir directo al checkout.\nfunction doltendixAddToCart(link) {\n  if (link.classList.contains('is-loading')) return;\n\n  const productId = link.dataset.productId;\n  let quantity = '1';\n  try {\n    quantity = new URL(link.href, window.location.href).searchParams.get('quantity') || '1';\n  } catch (err) {}\n\n  const labelEl = link.querySelector('.cta-label');\n  const originalLabel = labelEl ? labelEl.textContent : '';\n\n  \/\/ Fija el ancho actual del bot\u00f3n para que no \"salte\" al cambiar el texto.\n  link.style.minWidth = link.offsetWidth + 'px';\n\n  link.classList.add('is-loading');\n  if (labelEl) labelEl.textContent = 'Adding\u2026';\n\n  const body = new URLSearchParams();\n  body.set('product_id', productId);\n  body.set('quantity', quantity);\n\n  \/\/ URL relativa: pega siempre al mismo dominio\/subdominio con el que se\n  \/\/ carg\u00f3 la p\u00e1gina (evita bloqueos de CORS si el sitio usa www vs. sin www).\n  fetch('\/?wc-ajax=add_to_cart', {\n    method: 'POST',\n    credentials: 'same-origin',\n    headers: { 'Content-Type': 'application\/x-www-form-urlencoded' },\n    body: body.toString()\n  })\n    .then(res => res.text().then(text => ({ status: res.status, text: text })))\n    .then(({ status, text }) => {\n      let data;\n      try {\n        data = JSON.parse(text);\n      } catch (parseErr) {\n        console.error('Doltendix: la respuesta de add_to_cart no es JSON (status ' + status + ')', text.slice(0, 600));\n        throw new Error('invalid_json');\n      }\n\n      if (!data || data.error) {\n        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data.cart_hash, $link]);\n          window.jQuery(document.body).trigger('wc_fragments_refreshed');\n        }\n        document.body.dispatchEvent(new CustomEvent('added_to_cart', { detail: data }));\n      } catch (triggerErr) {\n        console.error('Doltendix: el agregado funcion\u00f3 pero un listener de \"added_to_cart\" tir\u00f3 error', triggerErr);\n      }\n\n      link.classList.remove('is-loading');\n      if (labelEl) {\n        labelEl.textContent = 'Added!';\n        setTimeout(() => {\n          labelEl.textContent = originalLabel;\n          link.style.minWidth = '';\n        }, 1600);\n      }\n    })\n    .catch(err => {\n      console.error('Doltendix: fallo el agregado por AJAX, redirigiendo al checkout', err);\n      \/\/ Si el agregado por AJAX falla de verdad, seguimos con el flujo cl\u00e1sico: ir al checkout.\n      window.location.href = link.href;\n    });\n}\n\ndocument.querySelectorAll('.doltendix-buy-link').forEach(link => {\n  link.addEventListener('click', function (e) {\n    e.preventDefault();\n    doltendixAddToCart(this);\n  });\n});\n<\/script>\n","protected":false},"excerpt":{"rendered":"<p>Doltendix\u00ae | Dietary supplement for tendons and ligaments \u2014 Kolinpharma ES EN Kolinpharma\u00ae \u00b7 Leader to Health Specialized nutrition for 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